Figure 7From: Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB Immunostaining-positive areas of Nrf2, HO-1, NQO1 and 8-OHdG in the kidneys of normal, CKD, and AST-120-treated CKD rats. Data are expressed as mean±SE (n=9). **P < 0.01, ***P < 0.001 vs. normal rats; # P<0.05, ## P<0.01, ### P<0.001 vs. CKD rats.Back to article page