Table 2 Determinants for ESA resistance (Q4 ERI > 10.1): univariate analyses
From: Predicting erythropoietin resistance in hemodialysis patients with type 2 diabetes
Characteristic | OR | 95% CI (lower and upper limit) | P-value | |
|---|---|---|---|---|
Age years | 1,02 | 1,00 | 1,04 | 0,05 |
Male sex | 1,76 | 1,32 | 2,35 | <0,001 |
Time on HD months | 0,96 | 0,94 | 0,99 | 0,002 |
Smoker or ex-smoker | 0,76 | 0,57 | 1,02 | 0,07 |
BMI kg/m2 | 0,97 | 0,94 | 1,00 | 0,06 |
Heart Rate bpm | 1,01 | 1,00 | 1,02 | 0,02 |
History of CHF % | 1,52 | 1,14 | 2,04 | 0,01 |
Use of ACE-Inhibitors % | 1,27 | 0,96 | 1,69 | 0,09 |
Laboratory values | Â | Â | Â | Â |
Iron saturation % | 0,94 | 0,93 | 0,96 | <0,001 |
Ferritin ug/l | 1,00 | 0,99 | 1,00 | 0,01 |
Albumin g/dl | 0,22 | 0,14 | 0,36 | <0,001 |
Urea mg/dl | 0,99 | 0,99 | 1,00 | 0,01 |
Potassium mmol/l | 1,24 | 1,05 | 1,46 | 0,01 |
Glucose mg/dl | 1,00 | 1,00 | 1,01 | 0,03 |
LDL-C mg/dl | 0,99 | 0,99 | 1,00 | 0,03 |
AP U/l | 1,64 | 1,15 | 2,36 | 0,01 |
Biomarker | Â | Â | Â | Â |
NT-pro-BNP pg/ml | 1,21 | 1,08 | 1,35 | 0,00 |
PTH ng/l | 0,86 | 0,75 | 0,99 | 0,04 |
CRP mg/l | 1,24 | 1,10 | 1,39 | 0,00 |
Troponin T ng/ml | 1,20 | 1,03 | 1,40 | 0,02 |
ADMA umol/l | 4,45 | 1,81 | 10,98 | 0,00 |
25(OH) vitamin D ng/ml | 0,75 | 0,55 | 1,02 | 0,07 |
Osteocalcin ug/l | 0,85 | 0,71 | 1,01 | 0,06 |