Predicting erythropoietin resistance in hemodialysis patients with type 2 diabetes

BMC Nephrology

Table 3 Predictors of ESA resistance

Predictors
	Model 1			Model 2			Model 3
	Clinical parameters			Model 1 plus routine laboratory			Model 2 plus specific biomarkers
	OR	95% CI	p-value	OR	95% CI	p-value	OR	95% CI	p-value
Sex (male)	1,72	1.27-2.32	<0.001	1,73	1.22-2.45	0.002	1,54	1.08-2.21	0.017
BMI (kg/m²)	0.97	0.94-1.00	0.048	0.96	0.93-0.996	0.03	0,96	0.92-0.99	0.02
dialysis vintage (mo)	0.97	0.95-0.99	0.011
CHF (%)	1,41	1.04-1.91	0.028	1,34	0.96-1.87	0.08	1,30	0.92-1.84	0.14
ACE-inhibitors (%)	1,32	0.98-1.78	0.071	1,33	0,96-1,84	0.09
heart rate (bpm)	1,01	1,00-1,02	0.052	1,01	1.00-1.02	0.029
albumin (g/dl)				0,29	0.17-0.52	<0.001	0,40	0.22-0.72	0.002
LDL-cholesterol (mg/dl)				0.996	0.99-1.001	0.125	0.995	0.989-1.001	0.098
creatinine (mg/dl)				1,08	0.99-1.17	0.087
urea (mg/dl)				0.996	0.991-1.001	0.10
iron saturation (%)				0,94	0.93-0.96	<0.001	0.95	0.93-0.97	<0.001
potassium (mmol/l)				1,21	0.99-1.47	0.062	1,34	1.09-1.64	0.005
CRP (mg/l)							1,18	1.02-1.38	0.028
Troponin T (ng/ml)							1,17	0.97-1.42	0.10
ADMA (umol/l)							5,24	1.75-15.70	0.003
Osteocalcin (ug/l)							0,82	0.66-1.01	0.064

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