Figure 1

Biomarker ProET-1 concentrations. Box plots representing proET-1 concentrations established in subjects with end-stage CKD (n = 20) and renal failure (n = 20). For comparison, results for a group of 20 apparently healthy subjects (REF) are depicted. The box extends form the 25^th to the 75^th percentile. The line inside the box indicates the median value. Whiskers extend to the largest and smallest observed values within 1.5 box lengths. Outlying values corresponding with values between 1.5 and 3 times the box length are designated as (0). The horizontal dashed line indicates the upper level of the reference range for apparently healthy subjects. Statistically significant deviations between groups (p < 0.05) are indicated by ∏.