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Table 1 PLT granules staining density and coagulation activation parameters in end-stage CKD subjects with proET-1 concentrations of <250 and >250 pMol/L

From: Coagulation activation, depletion of platelet granules and endothelial integrity in case of uraemia and haemodialysis treatment

  End-stage CKD
  proET-1 <250 pMol/L (n = 11) mean ± SD proET-1 >250 pMol/L (n = 9) mean (SD) statistical significance
proET-1 (pMol/L) 210 ± 18 285 ± 40 p = 0.000
PLTs with <25% granules staining density (%) 33 ± 13 46 ± 8 p = 0.008
PLTs with >75% granules staining density (%) 34 ± 15 18 ± 10 p = 0.001
TAT (μg/L) 3.8 ± 1.0 3.8 ± 1.4 NS
Fibrinogen (g/L) 4.1 ± 1.3 3.9 ± 1.2 NS
  1. Evaluation of proET-1, PLT granule staining density, TAT and fibrinogen (mean value with standard deviation) established in the group with end-stage CKD. Results of statistically significant evaluation are indicated as p-values.
  2. NS = deviation not statistically significant.