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Table 1 PLT granules staining density and coagulation activation parameters in end-stage CKD subjects with proET-1 concentrations of <250 and >250 pMol/L

From: Coagulation activation, depletion of platelet granules and endothelial integrity in case of uraemia and haemodialysis treatment

 

End-stage CKD

 

proET-1 <250 pMol/L (n = 11) mean ± SD

proET-1 >250 pMol/L (n = 9) mean (SD)

statistical significance

proET-1 (pMol/L)

210 ± 18

285 ± 40

p = 0.000

PLTs with <25% granules staining density (%)

33 ± 13

46 ± 8

p = 0.008

PLTs with >75% granules staining density (%)

34 ± 15

18 ± 10

p = 0.001

TAT (μg/L)

3.8 ± 1.0

3.8 ± 1.4

NS

Fibrinogen (g/L)

4.1 ± 1.3

3.9 ± 1.2

NS

  1. Evaluation of proET-1, PLT granule staining density, TAT and fibrinogen (mean value with standard deviation) established in the group with end-stage CKD. Results of statistically significant evaluation are indicated as p-values.
  2. NS = deviation not statistically significant.
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BMC Nephrology

ISSN: 1471-2369

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