Table 1 Patient characteristics
From: Impact of non-dialysis chronic kidney disease on survival in patients with septic shock
Parameter | Overall | Non-CKD | CKD | p value between Non-CKD and CKD |
|---|---|---|---|---|
n=163 | n=107 | n=56 | ||
Male gender | 93 (57%) | 58 (54%) | 35 (62%) | 0.4 |
Age (years) | 66 (57–76) | 63 (54–76) | 72 (62–79) | <0.001 |
Diabetes | 51 (31%) | 20 (19%) | 31 (55%) | 0.001 |
HBP | 97 (59%) | 58 (54%) | 39 (70%) | 0.08 |
Heart failure | 26 (16%) | 7 (6%) | 19 (34%) | 0.001 |
Peripheral artery disease | 25 (15%) | 9 (8%) | 16 (28%) | 0.002 |
Coronary artery disease | 28 (17%) | 11 (10%) | 17 (30%) | 0.003 |
COPD | 27 (17%) | 18 (17%) | 9 (16%) | 0.9 |
Statin use | 41 (25%) | 20 (19%) | 21 (37%) | 0.01 |
Admission | ||||
not related to surgery | 145 (89%) | 97 (91%) | 48 (86%) | 0.5 |
related to surgery | 18 (11%) | 10 (9%) | 8 (14%) | 0.4 |
ICU-acquired septic shock | 11 (7%) | 8 (7%) | 3 (5%) | 0.8 |
Baseline eGFR, (ml/min/1.73m2) | 67 (44–92) | 81 (67–108) | 36 (28–44) | <0.001 |
Scr on admission (μmol/l) | 241 (137–415) | 187 (116–305) | 400 (300–520) | <0.001 |
Scr onset of septic shock (μmol/l) | 240 (131–390) | 203 (102–332) | 380 (236–469) | <0.001 |
Hb on admission (g/dl) | 10.2 (8.7-12.1) | 10.2 (8.6-12.2) | 10.2 (8.9-11.8) | 0.6 |
SAPS II | 60 (45–78) | 58 (43–69) | 66 (55–85) | 0.005 |
Days w/o catechol (days) | 2 (0–9) | 3 (0–9) | 0 (0–5) | 0.02 |
Days w/o MV (days) | 1 (0–5) | 2 (0–5) | 1 (0–5) | 0.9 |
Length of stay (days) | 7 (3–14) | 8 (3–15) | 5 (2–13) | 0.1 |
Infection sites | ||||
lungs | 64 (39%) | 43 (40%) | 21 (37%) | 0.9 |
abdominal | 25 (15%) | 16 (15%) | 9 (16%) | 0.9 |
urinary | 21 (13%) | 12 (11%) | 9 (16%) | 0.5 |
cutaneous | 12 (7%) | 8 (7%) | 4 (7%) | 0.8 |
endocarditis | 2 (1%) | 0 | 2 (3%) | - |
bone | 2 (1%) | 1 (1%) | 1 (2%) | - |
unknown | 35 (21%) | 25 (23%) | 10 (20%) | 0.5 |
RIFLE Classification | 135 (83%) | 86 (80%) | 49 (87%) | 0.4 |
Risk | 25 (17%) | 23 (21%) | 2 (3%) | <0.001 |
Injury | 26 (19%) | 16 (15%) | 10 (18%) | 0.3 |
Failure | 78 (58%) | 47 (44%) | 31 (63%) | 0.08 |
Loss of function | 6 (4%) | 0 | 6 (12%) | - |
ESKD | 0 | 0 | 0 | - |
Renal support | 75 (46%) | 45 (42%) | 30 (53%) | 0.3 |
IHD | 46 (33%) | 29 (64%) | 17 (57%) | 0.9 |
CVVHDF | 32 (23%) | 19 (42%) | 13 (43%) | 0.6 |
CVVHF | 16 (11%) | 12 (27%) | 4 (13%) | 0.5 |
28-day mortality | 93 (57%) | 54 (50%) | 39 (70%) | 0.03 |
1-year mortality | 115 (71%) | 69 (64%) | 46 (82%) | 0.03 |