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Table 1 Demographic, clinical, and biochemical data of IgAN patients

From: Poor histological lesions in IgA nephropathy may be reflected in blood and urine peptide profiling

 

IgAN patients

At the time of initial biopsy

At the end of follow-up

Number of patients

19

Age, years

42 (33–52)

44 (35–54)

Gender (Male), n (%)

15 (79)

Hypertension (Yes), n (%)

12 (63)

Diabetes (Yes), n (%)

1 (5)

Dyslipidemia (Yes), n (%)

9 (47)

Serum creatinine, mg/dl

2.00 (1.40-2.57)

3.16a (1.26-6.18)

Uric acid, mg/dl

7.40 (5.45-8.30)

7.40 (6.55-9.20)

Serum albumin, g/l

34.00 (31.00–39.00)

40.00a (36.75–42.40)

Cholesterol, mg/dl

194.00 (157.00–221.75)

147.00a (131.50-213.00)

Proteinuria, g/24 hours

2.28 (1.20-4.26)

1.30 (0.52-3.27)

RAAS blockade (Yes), n (%)

7 (37)

17 (89)

ACEI

5 (26)

11(58)

ARB

1 (5)

3(16)

ACEI plus ARB

1 (5)

3(16)

Statins (Yes), n (%)

4 (21)

9 (47)

  1. Data are expressed as median and ranges. aSignificant Wilcoxon test (P < 0.05) in IgAN patients between the time of initial biopsy and the end of follow-up. RAAS: renin-angiotensin-aldosterone system; ACEI: angiotensin-converting enzyme inhibitors; ARB: angiotensin II receptor blockers.