Table 1 Physiologic parameters of experimental animals

Body weight (g)

 Initial

205 ± 8

204 ± 9

199 ± 10

 Final

563 ± 34

493 ± 29*

475 ± 31*

Blood glucose (mg/dl)

 Initial

111 ± 11

100 ± 10

111 ± 6

 Final

180 ± 9

184 ± 21

172 ± 21

BUN (mg/dl)

 Initial

8.27 ± 2.48

8.63 ± 1.56

9.94 ± 3.41

 Final

12.17 ± 2.50

28.19 ± 3.56*

25.04 ± 7.12*

Cr (mg/dl)

 Initial

0.39 ± 0.08

0.42 ± 0.06

0.39 ± 0.11

 Final

0.52 ± 0.04

0.90 ± 0.09*

0.70 ± 0.19*^#

Cl_Cr (ml/min/100 g)

 Initial

0.62 ± 0.25

0.52 ± 0.09

0.78 ± 0.33

 Final

0.48 ± 0.05

0.31 ± 0.03*

0.43 ± 0.12^#