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Table 2 Comparison of the clinical and pathologic parameters between patients with and without elevated urinary KIM-1/Cr

From: Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria

Variable

Without elevated urinary KIM-1/Cr (n = 33)

With elevated urinary KIM-1/Cr (n = 18)

P value

Male/female (n)

11/22

8/10

0.547

Age (years)

30.03 ± 7.96

27.33 ± 7.89

0.252

Time from onset (months)

5(0.5, 60)

3(0.33, 84)

0.501

With/without prior infection

13/20

10/8

0.378

With/without gross hematuria

16/17

9/9

1.000

Systolic blood pressure (mmHg)

118.18 ± 10.95

115.28 ± 13.98

0.416

Diastolic blood pressure (mmHg)

74.24 ± 8.11

71.11 ± 10.51

0.241

Proteinuria (g/24 h)

0.52 ± 0.20

0.62 ± 0.24

0.149

Serum creatinine (μmol/L)

74.24 ± 13.09

75.69 ± 13.10

0.707

eGFR(ml/min/1.73 m2)

105.24 ± 23.19

104.56 ± 16.27

0.912

Serum IgA (mg/dL)

318.05 ± 111.82

374.27 ± 127.36

0.180

Serum Complement 3 (mg/dL)

93.73 ± 23.15

96.38 ± 19.04

0.774

Mesangial hypercellularity (M0/M1)

29/4

13/5

0.249

Segmental glomerulosclerosis (S0/S1)

28/5

17/1

0.405

Endocapillary hypercellularity (E0/E1)

29/4

15/3

0.686

Tubular atrophy/interstitial fibrosis (T0/T1/T2)

33/0/0

13/5/0

0.004*

With/without extracapillary proliferation (cresecents)

6/27

9/9

0.026*

With/without global glomerulosclerosis

13/20

10/8

0.378

With/without vascular lesions

6/27

8/10

0.057

  1. *Being statistically significant. Since there was no patient with T2 in two groups, distribution of the variable of tubular atrophy/interstitial fibrosis was compared by chi-square test.