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Table 2 Comparison of the clinical and pathologic parameters between patients with and without elevated urinary KIM-1/Cr

From: Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria

Variable Without elevated urinary KIM-1/Cr (n = 33) With elevated urinary KIM-1/Cr (n = 18) P value
Male/female (n) 11/22 8/10 0.547
Age (years) 30.03 ± 7.96 27.33 ± 7.89 0.252
Time from onset (months) 5(0.5, 60) 3(0.33, 84) 0.501
With/without prior infection 13/20 10/8 0.378
With/without gross hematuria 16/17 9/9 1.000
Systolic blood pressure (mmHg) 118.18 ± 10.95 115.28 ± 13.98 0.416
Diastolic blood pressure (mmHg) 74.24 ± 8.11 71.11 ± 10.51 0.241
Proteinuria (g/24 h) 0.52 ± 0.20 0.62 ± 0.24 0.149
Serum creatinine (μmol/L) 74.24 ± 13.09 75.69 ± 13.10 0.707
eGFR(ml/min/1.73 m2) 105.24 ± 23.19 104.56 ± 16.27 0.912
Serum IgA (mg/dL) 318.05 ± 111.82 374.27 ± 127.36 0.180
Serum Complement 3 (mg/dL) 93.73 ± 23.15 96.38 ± 19.04 0.774
Mesangial hypercellularity (M0/M1) 29/4 13/5 0.249
Segmental glomerulosclerosis (S0/S1) 28/5 17/1 0.405
Endocapillary hypercellularity (E0/E1) 29/4 15/3 0.686
Tubular atrophy/interstitial fibrosis (T0/T1/T2) 33/0/0 13/5/0 0.004*
With/without extracapillary proliferation (cresecents) 6/27 9/9 0.026*
With/without global glomerulosclerosis 13/20 10/8 0.378
With/without vascular lesions 6/27 8/10 0.057
  1. *Being statistically significant. Since there was no patient with T2 in two groups, distribution of the variable of tubular atrophy/interstitial fibrosis was compared by chi-square test.