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Table 3 R2* values in the control group and in the type 2 diabetic nephropathy groups injected with iodinated contrast agents

From: Effects of iodinated contrast agents on renal oxygenation level determined by blood oxygenation level dependent magnetic resonance imaging in rabbit models of type 1 and type 2 diabetic nephropathy

Kidney tissue Treatment 1 h 24 h 48 h 72 h
Cortex CG 19.0 ± 2.3 18.9 ± 2.1 19.2 ± 2.2 18.9 ± 2.7
  DN PC 24.5 ± 3.6* 24.5 ± 4.3* 24.7 ± 4.5* 25.4 ± 3.7*
  DN 200 31.1 ± 3.2* 31.3 ± 4.9* 30.9 ± 3.6* 28.9 ± 4.3*
  DN 240 33.3 ± 4.6* 34.8 ± 4.8* 34.0 ± 3.1* 33.5 ± 7.9*
  DN 300 41.7 ± 5.1* 41.9 ± 3.4* 40.1 ± 5.5* 39.2 ± 4.0*
  DN 350 46.7 ± 5.2* 50.2 ± 5.8* 48.9 ± 5.7* 43.7 ± 6.0*
  DN 400 50.1 ± 5.6* 57.6 ± 5.3* 53.9 ± 6.1* 47.4 ± 5.5*
Outer medulla CG 20 ± 4.2 22.7 ± 4.8 22.4 ± 5.4 21.6 ± 5.1
  DN PC 29.9 ± 4.4* 30.7 ± 5.1* 28.2 ± 5.8* 29.5 ± 5.4*
  DN 200 38.1 ± 4.6* 40.1 ± 6.2* 37.5 ± 4.8* 33.8 ± 5.8*
  DN 240 42.3 ± 3.5* 43.3 ± 5.7* 40.3 ± 4.2* 37.3 ± 3.5*
  DN 300 53.4 ± 5.2* 57.9 ± 5.6* 48.8 ± 4.8* 45.4 ± 5.2*
  DN 350 60.6 ± 6.3* 72.4 ± 5.7* 62.9 ± 5.5* 56.5 ± 5.3*
  DN 400 67.6 ± 5.6* 80.4 ± 6.3* 74.7 ± 6.1* 67.7 ± 5.8*
Inner medulla CG 20.2 ± 2.4 20.0 ± 3.6 21.8 ± 2.7 20.5 ± 3.2
  DN PC 22.7 ± 4.7* 24.5 ± 3.8* 24.3 ± 4.0* 22.9 ± 3.4*
  DN 200 27.2 ± 3.3* 30.6 ± 4.0* 26.2 ± 2.7* 25.0 ± 3.5*
  DN 240 30.4 ± 3.8* 33.6 ± 5.8* 31.9 ± 4.2* 29.9 ± 5.2*
  DN 300 42.8 ± 5.2* 44.2 ± 5.0* 38.8 ± 4.9* 32.7 ± 4.8*
  DN 350 49.2 ± 5.7* 50.2 ± 4.8* 47.3 ± 5.8* 39.4 ± 5.1*
  DN 400 55.2 ± 5.4* 57.2 ± 5.3* 55.3 ± 6.3* 46.4 ± 5.7*
  1. Abbreviations: CG control group, DN diabetic nephropathy, PC positive control; 200 200 mg I/mL contrast agent; 240 240 mg I/mL contrast agent, 300 300 mgI/mL contrast agent, 350 350 mg I/mL contrast agent, 400 400 mg I/mL contrast agent.
  2. The control group and the DN PC group were injected with physiological saline/.
  3. Values are means ± standard deviation.
  4. *P < 0.05 vs. the control group.