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Table 8 Concordance correlation coefficients (and 95% confidence intervals) for 3 processes using 5 methods based on Cystatin C assay

From: Assessing the agreement of biomarker data in the presence of left-censoring

Processes Method 1 Method 2 Method 3 Method 4 Method 5
Delete the pair Replace by LOD Replace by 0.5 × LOD Replace by c× LOD ML
A (Initial 48 hours: 4°C vs- 80°C) 0.9348 (0.89, 0.98) 0.9641 (0.94, 0.98) 0.9641 (0.94, 0.98) 0.9641 (0.94, 0.98) 0.9735 (0.95, 0.99)
B (Initial 48 hours: 25°C vs −80°C) 0.9320 (0.89, 0.98) 0.9514 (0.92, 0.98) 0.9514 (0.92, 0.98) 0.9514 (0.92, 0.98) 0.9471 (0.91, 0.98)
C (Centrifuge vs No Centrifuge) 0.9985 (0.99, 1.00) 0.9982 (0.99, 1.00) 0.9758 (0.96, 0.99) 0.9653 (0.95, 0.98) 0.9999 (0.99, 1.00)