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Table 2 Laboratory data stratified by eGFR values

From: Association of serum levels of FGF23 and α-Klotho with glomerular filtration rate and proteinuria among cardiac patients

 

eGFR ≥60 mL/min/m2

eGFR 30–60 mL/min/m2

eGFR <30 mL/min/m2

 

Variables

(n = 44)

(n = 124)

(n = 17)

P value

eGFR, mL/min/1.73 m2

 

69.2 ± 8.7

 

45.9 ± 8.4

 

25.6 ± 8.4

<0.001

Urine albumin creatinine ratio

10

(7–55)

13

(6–27)

75

(10–196)

0.036

Serum cCa, mg/dL

9.1

(8.8 - 9.5)

9.1

(8.7 - 9.3)

9.1

(8.7 - 9.3)

0.508

Serum inorganic phosphate, mg/dL

3.40

(3.10 - 3.70)

3.30

(2.90 - 3.70)

3.30

(3.00 - 3.65)

0.546

Urine calcium creatinine ratio, mg/g

0.11

(0.07 - 0.17)

0.07

(0.04 - 0.11)

0.03

(0.01 - 0.05)

<0.001

Fractional excretion of calcium, %

0.81

(0.48 - 1.30)

0.72

(0.42 - 1.05)

0.46

(0.17 - 0.89)

0.041

Urine phosphate creatinine ratio, mg/g

 

0.50 ± 0.23

 

0.49 ± 0.20

 

0.39 ± 0.15

0.149

TRP, %

 

90.1 ± 4.9

 

85.5 ± 6.2

 

80.2 ± 8.6

<0.001

TmP/GFR, mg/dL

3.3

(2.8 - 4.2)

2.8

(2.5 - 3.4)

2.6

(2.2 - 3.2)

<0.001

FGF23, pg/mL

41.2

(29.4 - 62.3)

47.0

(35.3 - 67.9)

66.4

(45.6 - 111.3)

0.009

α-Klotho, mg/dL

425

(254–539)

351

(224–473)

211

(163–286)

0.001