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Table 2 Number of individuals free of or with coronary heart disease (CHD) at baseline who died or incurred cardiopulmonary events at follow-up, stratified to quartiles of eGFR (by CKD-EPI)

From: Renal “hyperfiltrators” are at elevated risk of death and chronic diseases

 

Total “healthy” sample

CHD at baseline

 

Total subjects

p = 0.37 Deaths

Nonfatal Events

Total subjects

p = 0.036 Deaths

Nonfatal Events

Quartile 1

117

1

4

81

3

14

Quartile 2

119

4

4

75

 

16

Quartile 3

116

6

3

83

1

19

Quartile 4

117

5

7

81

5

8

Grand total

469

16¶

18*

320

57‡

  1. *As nonfatal events heart failure occurred in 13, chronic obstructive pulmonary disease (COPD) in 5 (all in quartiles 3 & 4) unique subjects
  2. ‡ Nonfatal myocardial infarction (MI) in 23, heart failure in 24, COPD in 8, stroke in 2 subjects.
  3. ¶ Death was due to MI in 6, heart failure in 5 patients, stroke and COPD in 2 patients each, lung cancer in 4, breast cancer in 2 patients, cardiomyopathy and leg amputation in 1 patient each. Cause remained obscure in 2 instances.