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Table 1 Comparison of clinical and demographic data between patients with a MBL level above or below the median

From: High levels of mannose-binding lectin are associated with lower pulse wave velocity in uraemic patients

 

MBL < 722 ug/L

MBL >722 ug/L

 

N = 49

N = 49

Age (years)

45.3 ± 13.0

41.6 ± 12.4

ESRD (months)

29 (0–168)

33 (0–120)

Dialysis status:

  

Haemodialysis (N)

34

32

Peritoneal dialysis (N)

13

13

Pre-dialysis (N)

2

4

Haemodialysis, venous access: Arterio-venous fistulae/permanently haemodialysis catheter (N)

15/19

15/17

Tx status (living donor/deceased donor)

22/27

26/23

Myocardial infarction (N)

2

2

Smoking (N)

15

14

Stroke (N)

3

2

Diabetes (N)

3

5

Impaired fasting glucose (N)

1

2

Impaired glucose tolerance (N)

21

13

Normal glucose tolerance (N)

24

29

Fasting plasma glucose (mmol/L)

5.0 ± 0.4

5.1 ± 0.5

OGTT 120min(mmol/L)

8.0 ± 2.1

7.7 ± 2.1

ISI (index)

7.4 ± 4.1

7.9 ± 4.9

BMI (kg/m2)

24.2 ± 3.8

24.5 ± 3.6

PWV (m/s)

8.2 (5.6-15.8)

6.8 (5.2-16.4)*

AIX (%)

27 (-10;56)

20 (-7;50)

FMD (%)

3.8 (-8.3;19.2)

3.5 (-6.8;19.1)

NID (%)

10.5 (2.9;27.1)

11.5 (2.0;27.2)

Systolic blood pressure (mmHg)

143 ± 25

140 ± 19

Diastolic blood pressure (mmHg)

85 ± 12

84 ± 13

Number of antihypertensive drugs

2 (0–5)

3 (0–6)*

P-C-reactive protein (mg/L)

2 (1–40)

2 (1–21)

P-Homocystein (umol/L)

21 (11–62)

22 (12–150)

P-PTH (pmol/L)

21 (2–100)

20 (4–156)

P-ionized calcium (mmol/L)

1.19 ± 0.09

1.21 ± 0.09

P-phosphate (mmol/L)

1.8 ± 0.4

2.0 ± 0.6

  1. Data are presented as mean (SD) or median and range.
  2. MBL: Mannose Binding Lectin, ESRD: end-stage renal disease,
  3. Tx: transplantation, BMI: body mass index, PTH: parathyroidea hormone,
  4. OGTT: oral glucose tolerance index, ISI: insulin sensitivity index.
  5. PWV: pulse wave velocity,
  6. AIX: Augmentation Index, FMD: flow mediated vasodilatation,
  7. NID: nitroglycerin independent dilatation,
  8. *P < 0.05.