Table 3 Definition and method of attainment of study outcomes
Author, Year published | Proteinuria definition | Proteinuria method | Hypertension definition | Hypertension method | Abnormal GFR definition | GFR estimation method |
|---|---|---|---|---|---|---|
Askenazi [14], 2006 | Urine alb/UCr ratio > 30 mg/g | NS | sys or dia >95% for age, sex, ht. HTN confirmed with 2 repeat visits | NS | GFR <90 | Schwartz formula |
Buysse [50], 2008 | UPr/UCr >0.2 mg/mg | Avg of 3 first morning samples | sys > 95% for age, sex, ht | Avg of 3 BP measurements | GFR <90 | Schwartz or Cockroft formula |
Georgaki-Angelaki [45], 1989 | NS | dipstick | abnormal BP for age | NS | GFR <90 | Inulin Clearance |
Mammen [41], 2012 | Urine alb/UCr ratio ≥ 30 mg/g | Spot collection. If positive, first morning sample | sys or dia >95% for age, sex, ht. HTN confirmed with ABPM or 2 repeat visits | lowest of 3 BP readings | GFR ≤90 | Schwartz formula or DTPA clearance |
Mel [36], 2013 | NS | Urinalysis | BP >90% | NS | GFR <90 | Schwartz formula |
Miler, 1997 | NS | NS | NS | NS | GFR <90 | Schwartz formula |
Shaw [44], 1991 | NS | dipstick | sys or dia >95% for age, sex, ht. HTN confirmed with 2 repeat visits | NS | Abnormal mGFR | DTPA clearance |
Slack [51], 2005 | >150Â mg/day | 24Â hour collection | sys >95% for age, sex, ht | lowest of 3 BP readings | GFR <90 | EDTA clearance |
Viaud [46], 2011 | UPr/UCr >0.5Â mg/mg | NS | NS | NS | GFR <90 | EDTA clearance |
Wedekin [52], 2008 | NP | NP | NP | NP | abnormal SCr | Schwartz formula |