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Table 1 Patients characteristics separated by tertiles of the percentage of ECW BIA to TBW Watson

From: Association between ratio of measured extracellular volume to expected body fluid volume and renal outcomes in patients with chronic kidney disease: a retrospective single-center cohort study

Population characteristics

Percentage of ECWBIAto TBWWatson

P for ANOVA

 

Tertile 1 (n = 50) (27 men with <38.3% and 23 women with <37.0%)

Tertile 2 (n = 49) (26 men with 38.3%–41.0% and 23 women with 37.0%–39.4%)

Tertile 3 (n = 50) (27 men with ≥41.1% and 23 women with ≥39.5%)

Age, years

62.0 ± 16.6

61.8 ± 15.1

67.1 ± 16.4

0.18

Height, cm

159 ± 10

159 ± 11

161 ± 8

0.46

Weight, kg

61 ± 15

56 ± 12

56 ± 10

0.09

Body surface area, m2

1.62 ± 0.21

1.56 ± 0.21

1.58 ± 0.16

0.41

Body mass index, kg/m2

24.0 ± 4.2

22.0 ± 3.5

21.6 ± 2.9

<0.01

Underlying disease

    

Glomerulonephritis, n (%)

23 (46.0)

22 (45.0)

17 (34.0)

0.41

Diabetes mellitus, n (%)

4 (8.0)

7 (14.3)

13 (26.0)

<0.05

Nephrosclerosis, n (%)

9 (18.0)

10 (20.4)

9 (18.0)

0.94

ADPKD, n (%)

0 (0.0)

0 (0.0)

1 (2.0)

0.37

Others, n (%)

14 (28.0)

10 (20.4)

10 (20.0)

0.56

Systolic blood pressure, mmHg

127 ± 19

122 ± 17

129 ± 21

0.19

Diastolic blood pressure, mmHg

75 ± 11

71 ± 9

69 ± 10

<0.01

Pulse pressure, mmHg

52 ± 11

51 ± 13

60 ± 17

<0.01

Resistant high blood pressure, n (%)

6 (12.0)

12 (24.5)

19 (38.0)

<0.05

TBWBIA, L (% in BW)

30.1 ± 7.5

30.9 ± 7.2

32.7 ± 5.6

0.14

(49.6 ± 5.6)

(55.3 ± 5.6)

(58.7 ± 5.1)

(<0.001)

ICWBIA, L (% in BW)

18.4 ± 4.7

18.8 ± 4.6

19.7 ± 3.4

0.30

(30.2 ± 3.5)

(33.5 ± 3.8)

(35.2 ± 3.2)

(<0.001)

ECWBIA, L (% in BW)

11.7 ± 2.8

12.1 ± 2.6

13.1 ± 2.2

0.02

(19.3 ± 2.1)

(21.7 ± 2.0)

(23.4 ± 2.1)

(<0.001)

Serum creatinine, mg/dL

1.67 ± 1.17

1.76 ± 1.27

2.55 ± 1.78

<0.01

eGFRCKD-EPI, ml/min per 1.73 m2

71.7 ± 48.8

71.0 ± 52.7

48.9 ± 46.2

<0.05

Serum albumin, g/dL

4.1 ± 0.4

4.0 ± 0.4

3.7 ± 0.5

<0.001

Total cholesterol, mg/dL

200 ± 34

193 ± 36

191 ± 55

0.53

Triglycerides, mg/dL

147 ± 71

139 ± 95

129 ± 88

0.55

Fasting blood glucose, mg/dL

103 ± 19

132 ± 45

134 ± 42

<0.05

UPCR, g/g · Cr

0.9 ± 1.5

0.8 ± 1.3

1.6 ± 1.9

<0.05

Uric acid, >7.0 mg/dL in men or >6.0 mg/dL in women, n (%)

23 (46.9)

27 (55.1)

32 (64.0)

0.23

24-hour urinary urea nitrogen excretion, g/day

2.1 ± 1.0

2.5 ± 1.9

2.2 ± 1.5

0.40

24-hour urinary creatinine excretion, g/day

1.5 ± 1.1

1.6 ± 1.5

1.5 ± 0.8

0.81

24-hour urinary sodium excretion, mmol/day

143 ± 58

128 ± 50

130 ± 54

0.37

Furosemide, n (%)

5 (10.0)

6 (12.2)

18 (36.0)

<0.01

Other diuretics, n (%)

7 (14.0)

7 (14.3)

6 (12.0)

0.94

ACE inhibitors, n (%)

14 (28.0)

17 (34.7)

16 (32.0)

0.77

AT1-R blockers, n (%)

30 (60.0)

28 (57.1)

25 (50.0)

0.58

Other antihypertensives

20 (40.0)

25 (51.0)

31 (62.0)

0.09

  1. Abbreviations: TBW BIA total body water as measured by bioimpedance analysis, ICW BIA intracellular water as measured by bioimpedance analysis, ECW BIA extracellular water as measured by bioimpedance analysis, TBW Watson total body water calculated using the Watson formula, eGFR CKD-EPI estimated glomerular filtration rate using the Chronic Kidney Disease Epidemiology Collaboration equation, UPCR urinary protein-to-creatinine ratio, ACE inhibitors angiotensin-converting enzyme inhibitors, AT1-receptor blockers angiotensin II type 1 receptor blockers.