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Figure 3 | BMC Nephrology

Figure 3

From: Citrate confers less filter-induced complement activation and neutrophil degranulation than heparin when used for anticoagulation during continuous venovenous haemofiltration in critically ill patients

Figure 3

Concentration of myeloperoxidase (MPO) measured at inlet (C i ) and outlet (C o ) and total mass production rate (M tp ) over time (median and interquartile range). Results of generalized estimating equations (symbols: no anticoagulation ■ heparin ▲ citrate) for myeloperoxidase in A. Ci: increases over time (time, P < 0.001), most in the no anticoagulation group (P < 0.001 for interaction). Note the increase in the heparin group between T = 0 and T = 10 minutes (P = 0.024). B. Co: highest in the heparin group (P < 0.001) and increases over time (P < 0.001), most in the no anticoagulation group (P = 0.005 for interaction). C. Mtp: highest in the heparin group (P = 0.034).

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