Concentration of myeloperoxidase (MPO) measured at inlet (C
) and outlet (C
) and total mass production rate (M
) over time (median and interquartile range). Results of generalized estimating equations (symbols: ● no anticoagulation ■ heparin ▲ citrate) for myeloperoxidase in A. Ci: increases over time (time, P < 0.001), most in the no anticoagulation group (P < 0.001 for interaction). Note the increase in the heparin group between T = 0 and T = 10 minutes (P = 0.024). B. Co: highest in the heparin group (P < 0.001) and increases over time (P < 0.001), most in the no anticoagulation group (P = 0.005 for interaction). C. Mtp: highest in the heparin group (P = 0.034).