From: Do acute elevations of serum creatinine in primary care engender an increased mortality risk?
Model | Variable | Odds Ratio (95% CI) | P-value | |
---|---|---|---|---|
5 | No AKI | 1 | <0.001 | |
-AKI 1 | 18.8 (12.0, 29.7) | |||
-AKI 1a | 8.26 (54.4, 12.9) | |||
-AKI 2 | 88.7 (98.7, 145) | |||
-AKI 3 | 269 (148, 488) | |||
-AKI 3a | 24.4 (3.30, 181) | |||
6 | No AKI | 1 | <0.001 | |
-AKI 1 | 14.0 (8.84, 22.2) | |||
-AKI 1a | 4.42 (2.81, 6.97) | |||
-AKI 2 | 59.4 (35.7, 98.8) | |||
-AKI 3 | 233 (121, 447) | |||
-AKI 3a | 25.6 (3.33, 197) | |||
Female sex | 0.61 (0.44, 0.85) | <0.001 | ||
Age(*) | -Linear term | 0.61 (0.22, 1.68) | <0.001 | |
-Squared term | 1.09 (1.02, 1.17) | |||
7 | No AKI | 1 | <0.001 | |
-AKI 1 | 9.69 (5.91, 15.9) | |||
-AKI 1a | 3.99 (2.46, 6.49) | |||
-AKI 2 | 42.9 (24.5, 75.1) | |||
-AKI 3 | 237 (115, 490) | |||
-AKI 3a | 44.5 (4.83, 409) | |||
Female sex | 0.62 (0.44, 0.88) | 0.007 | ||
Age(*) | -Linear term | 0.39 (0.14, 1.10) | <0.001 | |
-Squared term | 1.13 (1.06, 1.22) | |||
Any malignancy | 3.62 (2.31, 5.67) | <0.001 | ||
CHF | 2.32 (1.36, 3.94) | 0.002 | ||
CPD | 1.07 (0.63, 1.82) | 0.81 | ||
Cerebrovascular disease | 0.48 (0.23, 0.98) | 0.05 | ||
Dementia | 4.88 (2.48, 9.60) | <0.001 | ||
Diabetes | 1.19 (0.75, 1.89) | 0.45 | ||
Hemiplegia or paraplegia | 2.87 (0.91, 9.09) | 0.07 | ||
Hypertension | 1.24 (0.85, 1.80) | 0.26 | ||
MI | 0.79 (0.39, 1.62) | 0.52 | ||
Solid tumour | 8.15 (4.53, 14.6) | <0.001 | ||
Mild liver disease | 2.48 (0.88, 7.01) | 0.09 | ||
PVD | 1.18 (0.58, 2.41) | 0.64 | ||
Peptic ulcer | 2.82 (1.00, 7.93) | 0.05 | ||
Renal disease | 0.48 (0.24, 0.96) | 0.04 | ||
Rheumatic disease | 0.63 (0.22, 1.81) | 0.39 | ||
Missing data | 1.45 (0.82, 2.54) | 0.20 | ||
GFR > 60 | 1 | 0.92 | ||
GFR 45 - < 60 | 0.95 (0.61, 1.48) | |||
GFR 30 - < 45 | 0.92 (0.53, 1.58) | |||
GFR < 30 | 1.24 (0.53, 2.91) | |||
Time measurement (†) | 0.84 (0.80, 0.89) | <0.001 | ||
8 | No AKI | 1 | <0.001 | |
-AKI 1 | 9.55 (5.89, 15.5) | |||
-AKI 1a | 3.63 (2.24, 5.87) | |||
-AKI 2 | 38.9 (22.8, 66.3) | |||
-AKI 3 | 163 (81.6, 327) | |||
-AKI 3a | 27.0 (3.00, 243) | |||
Female sex | 0.67 (0.48, 0.94) | 0.02 | ||
Age (*) | Linear term | 0.54 (0.20, 1.48) | <0.001 | |
Squared term | 1.10 (1.03, 1.18) | |||
Charlson | ≤0 | 1 | <0.001 | |
1-10 | 2.92 (1.73, 4.93) | |||
11+ | 5.95 (3.68, 9.64) | |||
No info | 1.97 (1.06, 3.66) | |||
GFR > 60 | 1 | 0.45 | ||
GFR 45 - < 60 | 0.80 (0.52, 1.23) | |||
GFR 30 - < 45 | 0.70 (0.41, 1.18) | |||
GFR < 30 | 0.69 (0.31, 0.56) | |||
Time measurement (†) | 0.84 (0.80, 0.88) | <0.001 |