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Table 2 Factors associated with eGFR in ADPKD patients *

From: Hyperuricemia and deterioration of renal function in autosomal dominant polycystic kidney disease

 

   Univariate

 

   Multivariate

 
 

Beta ± SE

p-value

Beta ± SE

p-value

Age (yr)

−1.208 ± 0.087

< 0.001

−0.986 ± 0.086

< 0.001

Female (vs. male)

−2.714 ± 2.520

0.282

−9.217 ± 2.224

< 0.001

Mean BP (mm Hg)

−0.229 ± 0.089

0.010

0.043 ± 0.073

0.558

sUA (mg/dL)

−6.282 ± 0.666

< 0.001

−5.117 ± 0.666

< 0.001

Albuminuria

−14.687 ± 5.160

0.005

−4.956 ± 3.890

0.204

TKV (mL)†

−19.524 ± 4.060

< 0.001

−12.782 ± 3.245

< 0.001

  1. *353 patients without hypouricemic medication. †transformed in logarithmic scale. eGFR, estimated glomerular filtration rate; ADPKD, autosomal dominant polycystic kidney disease; SE, standard error; BP, blood pressure; sUA, serum uric acid; TKV, total kidney volume.