|
Variable
|
Control
|
AIRF
|
5/6Nx
|
|---|
|
(n = 10)
|
(n = 10)
|
(n = 10)
|
|---|
|
Initial body weight (g)
|
324.4 ± 37.4
|
307.1 ± 30.8
|
307.9 ± 19.9
|
|
Final body weight (g)
|
366.1 ± 18.7
|
312.0 ± 17.2a
|
385.4 ± 59.8a,b
|
|
Food intake (g/day)
|
17.5 ± 1.4
|
16.8 ± 1.9
|
18.9 ± 0.7b
|
|
Urine output (ml)
|
11.4 ± 5.4
|
53.7 ± 11.2a
|
22.7 ± 6.7a,b
|
|
TCP-BP (mmHg)
|
119.7 ± 7.3
|
154.4 ± 20.4a
|
220.0 ± 19.5a,b
|
|
LVW/100 g BW
|
0.18 ± 0.01
|
0.21 ± 0.02a
|
0.21 ± 0.05
|
-
1Data expressed as mean ± SD.
- TCP-BP, Blood pressure, as measured by tail cuff plethysmography.
- Initial, Before Nx5/6 and adenine diet protocol.
- Final, At the sacrifice.
-
ap < 0.05 vs. Control; bp < 0.05 vs. AIRF.
