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Table 2 Biochemical data at the sacrifice

From: Mineral bone disorder in chronic kidney disease: head-to-head comparison of the 5/6 nephrectomy and adenine models

Variable

Control (n = 10)

AIRF (n = 10)

5/6Nx (n = 10)

Serum Cr (mg/dl)

0.6 ± 0.1

1.6 ± 0.3a

1.3 ± 0.6a

Creat Clear (ml/min)

2.55 ± 0.74

0.67 ± 0.25a

1.1 ± 0.46a,b

Serum iCa (mmol/L)

1.2 ± 0.1

1.1 ± 0.1

1.1 ± 0.1

uCa (mg/dl)

14 (8–17)

6 (4–8)

11 (5–50)

Serum P (mg/dl)

5.6 ± 0.9

7.4 ± 0.7a

6.7 ± 1.4

FeP (%)

9.1 ± 4.8

21.2 ± 11.0a

7.6 ± 4.6b

iPTH (pg/ml)

108 (47–315)

681 (163–1,604)a

572 (198–4,199)a

FGF23 (pg/ml)

157 (107–310)

784 (418–14.476)a

893 (649–2.609)a

Calcitriol (pg/ml)*

69.2 ± 17.3

88.0 ± 16.6

35.1 ± 20.0b

  1. Data expressed as mean ± SD or median (min-max).
  2. Creat Clear, Creatinine clearance; Serum iCa, Serum ionized calcium; uCa, Urinary calcium; Serum P, Serum phosphate. *Calcitriol was measured in pooled sera.
  3. P < 0.05 avs Control; bvs AIRF.