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Table 2 Biochemical data at the sacrifice

From: Mineral bone disorder in chronic kidney disease: head-to-head comparison of the 5/6 nephrectomy and adenine models

Variable Control (n = 10) AIRF (n = 10) 5/6Nx (n = 10)
Serum Cr (mg/dl) 0.6 ± 0.1 1.6 ± 0.3a 1.3 ± 0.6a
Creat Clear (ml/min) 2.55 ± 0.74 0.67 ± 0.25a 1.1 ± 0.46a,b
Serum iCa (mmol/L) 1.2 ± 0.1 1.1 ± 0.1 1.1 ± 0.1
uCa (mg/dl) 14 (8–17) 6 (4–8) 11 (5–50)
Serum P (mg/dl) 5.6 ± 0.9 7.4 ± 0.7a 6.7 ± 1.4
FeP (%) 9.1 ± 4.8 21.2 ± 11.0a 7.6 ± 4.6b
iPTH (pg/ml) 108 (47–315) 681 (163–1,604)a 572 (198–4,199)a
FGF23 (pg/ml) 157 (107–310) 784 (418–14.476)a 893 (649–2.609)a
Calcitriol (pg/ml)* 69.2 ± 17.3 88.0 ± 16.6 35.1 ± 20.0b
  1. Data expressed as mean ± SD or median (min-max).
  2. Creat Clear, Creatinine clearance; Serum iCa, Serum ionized calcium; uCa, Urinary calcium; Serum P, Serum phosphate. *Calcitriol was measured in pooled sera.
  3. P < 0.05 avs Control; bvs AIRF.