Table 2 Biochemical parameters and echocardiogram findings

GFR (mL/min)

106.8 ± 9.2

69.2 ± 6.1

42.9 ± 9.4

24.7 ± 7.5

10.9 ± 3.4

0.013

Creatinine (mg/dL)

64.1 ± 20.1

103.0 ± 19.4

126.6 ± 40.5

331.4 ± 148.4

497.3 ± 377.9

0.003

Troponin T (ng/mL)

0.12 ± 0.10

0.09 ± 0.04

0.41 ± 0.33

0.21 ± 0.09

0.59 ± 0.49

0.918

CK-MB (U/L)

7.3 ± 2.9

9.9 ± 3.6

13.1 ± 4.6

13.2 ± 3.7

17.2 ± 9.7

0.627

Hgb (g/dL)

123.1 ± 12.1

135.8 ± 13.9

127.6 ± 18.2

107.1 ± 23.7

93.2 ± 22.9

0.000

TC (mmol/L)

3.6 ± 1.2

5.3 ± 1.6

4.3 ± 1.1

4.4 ± 1.6

3.4 ± 0.9

0.159

LDL-C (mmol/L)

2.3 ± 0.9

2.9 ± 1.2

2.4 ± 0.7

2.5 ± 1.3

1.8 ± 0.6

0.257

hs-CRP (mg/dL)

0.6 ± 0.5

1.1 ± 0.7

1.7 ± 0.9

2.7 ± 1.2

4.9 ± 3.7

0.000

Cys C (mg/l)

0.6 ± 0.3

1.0 ± 0.4

1.4 ± 0.5

2.4 ± 1.2

3.7 ± 2.8

0.000

NT-proBNP (pg/mL)

307.6 ± 52.4

1013.8 ± 639.5

4305.5 ± 1054.5

9687.3 ± 3014.7

10636.8 ± 4016.9

0.000

LVEF (%)

62 ± 13

53 ± 13

48 ± 11

49 ± 10

46 ± 12

0.007

IVS (mm)

9.3 ± 1.5

10.8 ± 1.8

11.2 ± 1.3

11.9 ± 1.4

12.2 ± 1.8

0.021

LVPWT (mm)

9.3 ± 1.4

11.4 ± 2.3

10.6 ± 1.2

11.2 ± 1.7

12.0 ± 1.1

0.028

EDV (ml)

48.0 ± 3.0

48.8 ± 6.2

49.4 ± 5.9

50.5 ± 6.8

56.2 ± 5.6

0.046