Table 5 Comparisons of definition and outcome of early IgAN with the previous studies
From: Long-term prognosis of clinically early IgA nephropathy is not always favorable
Hong Kong (‘00) | Hong Kong (‘01) | China (‘08) | Europe (‘12) | Korea (‘14) | |
|---|---|---|---|---|---|
N | 45 (NA) | 72 (10%) | 177 (NA) | 141 | 153 (8.8%) |
Definition | Cr < 1.3 mg/dL | Cr < 120 μmol/L | eGFR > 90 mL/min | eGFR > 60 mL/min | eGFR > 60 mL/min |
Proteinuria < 0.4 g/day | Proteinuria < 0.4 g/day | Proteinuria < 0.4 g/day | Proteinuria < 0.5 g/day | Proteinuria < 0.5 g/day | |
HTN (-) | HTN (-) | HTN (-) | HTN (-) | ||
FU months | 123 (60 –180) | 84 (14–112) | 111 (109–205) | 108 (60– 180) | 95 (38–207) |
Age (years) | 29 (15–57) | 27 (15–50) | 38 ± 16 | 23 (5–71) | 26 (16–65) |
Outcome | |||||
ESRD | No | 1 patient | No | No | 6 patients |
Cr ↑ | 6 (13%) | 5 (7%) | 43 (24%) | 5 (3.5%) | 3 (2.1%) |
Proteinuria ↑ | 15 (34%) | 24 (33%) | 79 (46%) | 21 (14.9%) | 11 (18.3%) |
HTN | 11 (24%) | 19 (26%) | 68 (38%) | 23 (16.3%) | NA |
Remission | NA | 10 (14%) | 10 (6%) | 53 (38%) | 36 (25%) |