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Table 5 Comparisons of definition and outcome of early IgAN with the previous studies

From: Long-term prognosis of clinically early IgA nephropathy is not always favorable

 

Hong Kong (‘00)

Hong Kong (‘01)

China (‘08)

Europe (‘12)

Korea (‘14)

N

45 (NA)

72 (10%)

177 (NA)

141

153 (8.8%)

Definition

Cr < 1.3 mg/dL

Cr < 120 μmol/L

eGFR > 90 mL/min

eGFR > 60 mL/min

eGFR > 60 mL/min

Proteinuria < 0.4 g/day

Proteinuria < 0.4 g/day

Proteinuria < 0.4 g/day

Proteinuria < 0.5 g/day

Proteinuria < 0.5 g/day

HTN (-)

HTN (-)

HTN (-)

 

HTN (-)

FU months

123 (60 –180)

84 (14–112)

111 (109–205)

108 (60– 180)

95 (38–207)

Age (years)

29 (15–57)

27 (15–50)

38 ± 16

23 (5–71)

26 (16–65)

Outcome

     

ESRD

No

1 patient

No

No

6 patients

Cr ↑

6 (13%)

5 (7%)

43 (24%)

5 (3.5%)

3 (2.1%)

Proteinuria ↑

15 (34%)

24 (33%)

79 (46%)

21 (14.9%)

11 (18.3%)

HTN

11 (24%)

19 (26%)

68 (38%)

23 (16.3%)

NA

Remission

NA

10 (14%)

10 (6%)

53 (38%)

36 (25%)

  1. NA, not applicable; Cr, creatinine; eGFR, estimated glomerular filtration rate; HTN, hypertension; ESRD, end stage renal disease.