Figure 7
From: Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dahl/Rapp rats
The top panel showed a Western blot using an anti-caspase-8 polyclonal IgG, which recognized both procaspase-8 and the active enzyme. Active caspase-8 (about 20 kDa) was observed only in kidney cortex of S rats on the 8.0% NaCl diet for 21 days. The bottom panel showed a Western blot that used an anti-Bid polyclonal IgG, which also recognized the 13 and 15 kDa cleaved fragments of Bid (tBid). Fragments of Bid (tBid) were apparent in lysates of renal cortex of S rats on the 8.0% NaCl diet for 21 days. Each lane represented a single rat (n = 4 rats in each group).