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Table 3 Iron sucrose removal in a closed-loop system by high-flux or high-efficiency hemodialysis membranes over 240 minutes. (System B)

From: Determination of iron sucrose (Venofer) or iron dextran (DexFerrum) removal by hemodialysis: an in-vitrostudy

 

Iron Sucrose (Venofer®)

Study condition

SBS % iron concentration change

(mean ± SD)

Khd (hr-1)

(mean ± SD)

Dialysate Iron Recovery (mg)

(mean ± SD)

Clearance (ml/min)

(mean ± SD)

F80: 0 ml/hr UFR

-3.13 ± 0.06

-0.0001 ± 0.0000

13.82 ± 13.34

-0.76 ± 0.01

F80: 500 ml/hr UFR

-0.03 ± 1.15

0.0000 ± 0.0000

23.59 ± 3.96

0.05 ± 0.19

CA210: 0 ml/hr UFR

-1.41 ± 3.77

-0.0001 ± 0.0002

5.47 ± 1.52

-0.34 ± 0.92

CA210: 500 ml/hr UFR

-1.58 ± 3.08

-0.0003 ± 0.0002

2.79 ± 1.89

-1.08 ± 0.93

  1. SBS = simulated blood solution; UFR = ultrafiltration rate; Khd = hemodialysis elimination rate; % = percent; † = Clearance values that are positive relate to accumulation of substance from the system; negative clearance values represent removal of substance