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Table 2 Common genes altered by protein overload and diabetes

From: Alterations of renal phenotype and gene expression profiles due to protein overload in NOD-related mouse strains

Gene Name ID

Expression ratios

P values

 

T1/C1

T2/C2

T3/C3

D2/C4

D1/C4

T1/C1

T2/C2

T3/C3

D2/C4

D1/C4

tcp-1 [Genbank:D10606]

1

1.9

1

0.7

0.7

NS

5.3E-04

NS

0.002

3.5E-05

FKBP52 [Genbank:X17069]

1

0.8

0.8

0.7

0.8

NS

0.007

0.003

4.5E-05

0.01

VAPA [Genbank:BC003866]

0.7

1

1

0.7

0.7

0.002

NS

NS

7.2E-05

2.5E-04

Cox7b [Genbank:NM_025379]

0.8

1

1

0.7

0.8

0.01

NS

NS

2.4E-05

0.001

mtDNACtrlRNA [Genbank:U47435]

0.6

1

1

1

0.7

0.01

NS

NS

NS

5.9E-05

Slc25a3 [Genbank:BC018161]

0.7

1

1

0.8

1

0.02

NS

NS

0.004

NS

AcylCoAtrsp [Genbank:BC005616]

0.7

1

1

0.6

0.6

0.03

NS

NS

0.005

1.5E-04

RpL21 [Genbank:U93863]

0.8

1

1

0.7

0.8

0.03

NS

NS

5.2E-05

0.001

HistAcetyl [Genbank:AF319620]

0.7

1

0.7

0.7

0.6

0.04

NS

0.02

0.002

2.2E-04

Hmlg.apopts [Genbank:AK008911]

0.9

1

1

0.7

0.8

0.04

NS

NS

5.5E-04

9.6E-05

rib. prot. S23 [Genbank:AK012574]

1.3

1

1

0.5

0.6

0.04

NS

NS

2.8E-05

1.9E-04

  1. T1, T2, T3, treated animals and C1, C2, C3 controls are as in Table (1), NOD long-term diabetic (D2), NOD new-onset diabetic (D1), non-diabetic NOD control (C4). For each gene, the mean expression value ratio between treated (or diabetic) and control animals are represented. Student test p values obtained for every comparison are also shown.