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Table 8 Differences in immunohistochemical findings between ANCA (+) and ANCA (+) patients

From: Predictors of outcome in idiopathic rapidly progressive glomerulonephritis (IRPGN)

  ANCA (+) N = 26 ANCA (-) N = 8 p
I. Glomeruli    
PCNA(+) cells 36 ± 16 26 ± 16 NS
α-SMA(+)cells 34 ± 15 32 ± 19 NS
Monocytes/macrophages 15 ± 10 14 ± 10 NS
LFA-1β(+)cells 15 ± 6 10 ± 4 NS
TGF-β1 expression 1.14 ± 0.69 2.25 ± 0.96 0.05
ICAM-1 expression 1.53 ± 0.64 2.25 ± 0.96 NS(0.06)
C5b-9 expression 2.27 ± 0.96 2.25 ± 0.5 NS
II. Tubulointerstitium    
HLA-DR(+) cells 1207 ± 831 736 ± 300 NS
PCNA(+)cells 809 ± 170 581 ± 181 0.041
α-SMA(+)cells 728 ± 260 556 ± 318 NS
Monocytes/macrophages 570 ± 204 452 ± 156 NS
LFA-1β(+)cells 485 ± 149 517 ± 86 NS
ICAM-1 in tubules 34.2 ± 11.4 45.5 ± 12.5 NS
C5b-9 in tubules 32,3 ± 9,7 32,7 ± 8.16 NS
TGF-β1 in interstitium 1.73 ± 0.8 2 ± 1.41 NS
TGF-β1 in tubules 1.87 ± 0.83 2.25 ± 0.96 NS
ICAM-1in vessels 1,21 ± 0,42 1.0 ± 0.01 NS
C5b-9 in vessels 1.06 ± 0.25 1.01 ± 0.09 NS