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Figure 3 | BMC Nephrology

Figure 3

From: p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels

Figure 3

p21 is decreased in kidneys from male Han:SPRD rats. [top] Protein extracts in kidney cortical preparations from control (closed) and cystic (open) male and female Han:SPRD rats were immunoblotted with an anti-p21 and β-actin antibodies. Immunoblots were analyzed by densitometry with ImageJ as described in Methods. [bottom] p21 expression is presented as the ratio of intensity of p21 bands compared to intensity of actin bands presented as mean ± SEM. * p < 0.01 versus control of same gender. Values within each bar denote the number of animals utilized.

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