Figure 6

Immunoperoxidase staining demonstrating similar levels of NQO1 in podocytes of PodoTrsp ^-/- and control ( Trsp ^L/L ) mice. Consecutive 3 μm kidney sections from vehicle control, vehicle KO (PodoTrsp^-/-), STZ control, and STZ KO (PodoTrsp^-/-) mice were stained for NQO1 or Wt1 (to identify podocytes). Arrows indicate selected podocytes in the Wt1 and merged images, and indicate the identical positions in the NQO1 images. Incubations with normal IgG in place of the primary antibodies served as negative controls.