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Table 2 Odds of eGFR <75 or <60 ml/min/1.73 m 2 by APOL1 risk group and income category, N = 462

From: Apolipoprotein L1, income and early kidney damage

Model – Variables Odds Ratios for eGFR < 75 (95% Confidence Interval) n = 51 events P interaction ( APOL1 x Income) Odds Ratios for eGFR < 60 (95% Confidence Interval) n = 19 events P interaction ( APOL1 x Income)
  High-risk versus Low-risk APOL1 variants Lowest Income versus Higher Income Groups   High-risk versus Low-risk APOL1 variants Lowest Income versus Higher Income Groups  
Individual Variables       
APOL1 1.55 (0.91, 2.63) -----   2.59 (2.48, 2.70) -----  
Income ----- 1.80 (1.22, 2.67)   ----- 1.09 (0.35, 3.41)  
Additive Models       
APOL1, Income Category 1.54 (0.91, 2.61) 1.80 (1.23, 2.63) 0.903 2.59 (2.47, 2.71) 1.08 (0.36, 3.22) 0.06
+ Age, Sex, Percent European ancestry 1.50 (0.90, 2.49) 1.81 (1.21, 2.72) 0.653 2.48 (2.29, 2.68) 1.06 (0.33, 3.36) 0.09