Table 2 Odds of eGFR <75 or <60 ml/min/1.73 m 2 by APOL1 risk group and income category, N = 462
Model – Variables | Odds Ratios for eGFR < 75 (95% Confidence Interval) n = 51 events | P interaction ( APOL1 x Income) | Odds Ratios for eGFR < 60 (95% Confidence Interval) n = 19 events | P interaction ( APOL1 x Income) | ||
|---|---|---|---|---|---|---|
High-risk versus Low-risk APOL1 variants | Lowest Income versus Higher Income Groups | High-risk versus Low-risk APOL1 variants | Lowest Income versus Higher Income Groups | |||
Individual Variables | ||||||
APOL1 | 1.55 (0.91, 2.63) | ----- | 2.59 (2.48, 2.70) | ----- | ||
Income | ----- | 1.80 (1.22, 2.67) | ----- | 1.09 (0.35, 3.41) | ||
Additive Models | ||||||
APOL1, Income Category | 1.54 (0.91, 2.61) | 1.80 (1.23, 2.63) | 0.903 | 2.59 (2.47, 2.71) | 1.08 (0.36, 3.22) | 0.06 |
+ Age, Sex, Percent European ancestry | 1.50 (0.90, 2.49) | 1.81 (1.21, 2.72) | 0.653 | 2.48 (2.29, 2.68) | 1.06 (0.33, 3.36) | 0.09 |