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Table 2 eGFR calculations and subsequent CKD classification based on minimum and maximum serum creatinine results obtained for each pool

From: Routine serum creatinine measurements: how well do we perform?

Pool, μmol/L 1 2 3 4 5
35 70 112 296 934
Min and max Scr, μmol/L 27 53 59 80 104 124 274 313 868 990
eGFR, ml/min/1.73 m 2 child 6y 158 80a,b         
CKD stage G1 G2         
man 18y    140 124 90a,b 73 28 24 7 6
CKD stage    G1 G1 G1 G2 G4 G4 G5 G5
woman 18y    128 93 68 55a,b 21 18 5 4
CKD stage    G1 G1 G2 G3a G4 G4 G5 G5
man 65 y    101 89a,b 65a,b 52 20 17 5 4
CKD stage    G1 G2 G2 G3a G4 G4 G5 G5
woman 65y    92a,b 67 49a,b 39 15 13a,b 4 3
CKD stage    G1 G2 G3a G3b G4 G5 G5 G5
  1. The updated Schwartz formula was used for eGFR calculation in the 6 year old child with a length = 116.5 cm [8]. The CKP-EPI formula was used for eGFR calculations in adults [11] (see Methods section).
  2. (Grade 1) Normal GFR: ≥90 mL/min/1.73 m2, (Grade 2) Mild impairment: 60-89 mL/min/1.73 m2, (Grade 3a) Mild to moderate impairment: 45-59 mL/min/1.73 m2, (Grade 3b) Moderate to severe impairment: 30-44 mL/min/1.73 m2, (Grade 4) Severe impairment: 15-29 mL/min/1.73 m2 and (Grade 5) End stage renal disease: <15 mL/min/1.73 m2. In the absence of kidney damage, Grade 1 and 2 cannot be considered as CKD, but Grade 3 is always considered as CKD.
  3. aIndicates cases for which eGFR calculated for the minimum and maximum serum creatinine values classify patients in different CKD stages.
  4. bIndicates cases for which the calculated CKD stage is different from the CKD stage obtained when the target value of the pool is used.