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Table 2 Parameters of contractile responses of isolated second order branches and the main branch of the mesenteric artery

From: Effects of oxonic acid-induced hyperuricemia on mesenteric artery tone and cardiac load in experimental renal insufficiency

  Sham Sham+Oxo NX NX+Oxo
Small artery     
Norepinephrine     
pD2 (−log mol/l) 5.81 ± 0.08 6.00 ± 0.09 5.81 ± 0.09 5.87 ± 0.11
Maximal wall tension (mN/mm) 5.46 ± 0.17 5.82 ± 0.50 6.63 ± 0.54 6.58 ± 0.39
KCl     
pD2 (−log mol/l) 1.41 ± 0.01 1.42 ± 0.02 1.39 ± 0.02 1.39 ± 0.03
Maximal wall tension (mN/mm) 5.59 ± 0.43 5.93 ± 0.56 6.37 ± 0.49 6.84 ± 0.32
Main branch     
Norepinephrine     
pD2 (−log mol/l) 6.26 ± 0.14 5.97 ± 0.05 6.49 ± 0.13 6.64 ± 0.11
Maximal wall tension (mN/mm) 7.30 ± 0.49 8.60 ± 0.49 9.14 ± 0.63 9.64 ± 1.52
KCl     
pD2 (−log mol/l) 1.51 ± 0.02 1.51 ± 0.03 1.51 ± 0.03 1.53 ± 0.03
Maximal wall tension (mN/mm) 6.79 ± 0.85 7.01 ± 0.94 7.53 ± 0.67 8.02 ± 0.96
  1. Values are mean ± SEM, n = 10 for all groups. pD2 is the negative logarithm of the concentration of agonist producing 50% of the maximal response. P < 0.05 NX groups compared with Sham groups using two-way ANOVA.