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Table 2 Parameters of contractile responses of isolated second order branches and the main branch of the mesenteric artery

From: Effects of oxonic acid-induced hyperuricemia on mesenteric artery tone and cardiac load in experimental renal insufficiency

 

Sham

Sham+Oxo

NX

NX+Oxo

Small artery

    

Norepinephrine

    

pD2 (−log mol/l)

5.81 ± 0.08

6.00 ± 0.09

5.81 ± 0.09

5.87 ± 0.11

Maximal wall tension (mN/mm)

5.46 ± 0.17

5.82 ± 0.50

6.63 ± 0.54

6.58 ± 0.39

KCl

    

pD2 (−log mol/l)

1.41 ± 0.01

1.42 ± 0.02

1.39 ± 0.02

1.39 ± 0.03

Maximal wall tension (mN/mm)

5.59 ± 0.43

5.93 ± 0.56

6.37 ± 0.49

6.84 ± 0.32

Main branch

    

Norepinephrine

    

pD2 (−log mol/l)

6.26 ± 0.14

5.97 ± 0.05

6.49 ± 0.13

6.64 ± 0.11

Maximal wall tension (mN/mm)

7.30 ± 0.49

8.60 ± 0.49

9.14 ± 0.63

9.64 ± 1.52

KCl

    

pD2 (−log mol/l)

1.51 ± 0.02

1.51 ± 0.03

1.51 ± 0.03

1.53 ± 0.03

Maximal wall tension (mN/mm)

6.79 ± 0.85

7.01 ± 0.94

7.53 ± 0.67

8.02 ± 0.96

  1. Values are mean ± SEM, n = 10 for all groups. pD2 is the negative logarithm of the concentration of agonist producing 50% of the maximal response. P < 0.05 NX groups compared with Sham groups using two-way ANOVA.