Table 4 Risk ratios for attributed causes of lupus nephritis and other glomerulonephritis vs. other causes of ESRD, among U.S. ESRD patients initiating treatment 7/05–9/11: sensitivity analyses
Attributed cause of ESRD | Risk ratio* for attributed cause of ESRD (95% CI) | ||||
|---|---|---|---|---|---|
Diabetes and hypertension only as referent group | Additional adjustment for albumin | Among patients who never recovered renal function | Additional adjustment for age-squared | Additional adjustment for age × sex | |
Pre-ESRD care, yes vs. no (odds ratio) | |||||
All other causes | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
Lupus nephritis | 1.56 (1.46–1.66) | 2.02 (1.88–2.17) | 1.69 (1.59–1.81) | 1.71 (1.61–1.82) | 1.55 (1.46–1.65) |
Other glomerulonephritis | 1.06 (1.04–1.09) | 1.20 (1.17–1.23) | 1.20 (1.18–1.23) | 1.23 (1.20–1.25) | 1.22 (1.19–1.24) |
Informed of transplant options, yes vs. no (odds ratio) | |||||
All other causes | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
Lupus nephritis | 0.98 (0.91–1.06) | 1.16 (1.06–1.26) | 1.11 (1.02–1.20) | 1.13 (1.04–1.22) | 1.09 (1.01–1.18) |
Other glomerulonephritis | 1.07 (1.03–1.10) | 1.19 (1.14–1.23) | 1.20 (1.16–1.24) | 1.20 (1.16–1.24) | 1.19 (1.15–1.23) |
Time to placement on the kidney transplant waitlist (hazard ratio) | |||||
In 1st year of ESRD | Â | Â | Â | Â | Â |
All other causes | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
Lupus nephritis | 1.53 (1.43–1.63) | 1.53 (1.43–1.64) | 1.50 (1.41–1.59) | 1.44 (1.35–1.53) | 1.39 (1.31–1.48) |
Other glomerulonephritis | 2.01 (1.95–2.06) | 1.86 (1.81–1.92) | 1.88 (1.83–1.93) | 1.93 (1.88–1.98) | 1.91 (1.86–1.96) |
After 1st year of ESRD | Â | Â | Â | Â | Â |
All other causes | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
Lupus nephritis | 1.56 (1.45–1.67) | 1.69 (1.57–1.83) | 1.66 (1.54–1.78) | 1.57 (1.46–1.69) | 1.52 (1.42–1.63) |
Other glomerulonephritis | 1.36 (1.31–1.41) | 1.37 (1.32–1.42) | 1.38 (1.33–1.43) | 1.41 (1.36–1.46) | 1.39 (1.34–1.44) |
Permanent vascular access used/in place, yes vs. no (odds ratio) | |||||
All other causes | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
Lupus nephritis | 0.57 (0.53–0.60) | 0.63 (0.59–0.67) | 0.64 (0.60–0.69) | 0.73 (0.68–0.77) | 0.61 (0.57–0.65) |
Other glomerulonephritis | 0.97 (0.95–0.99) | 1.10 (1.07–1.12) | 1.09 (1.06–1.11) | 1.14 (1.12–1.17) | 1.10 (1.07–1.12) |