Table 1 Laboratory and anthropometric measurements data of investigated groups: BMI > 30 (n = 36), CKD (n = 14) and control (n =25)

Age [years]

52,6 ± 8,4

66,8 ± 9,9

53,2 ± 10,5

1-2 p = 0,0009

1-3 p = 0,9672

2-3 p = 0,0015

Weight [kg]

102,5 ± 14,8

79,2 ± 15,3

68,1 ± 10,6

1-2 p = 0,0003

1-3 p = 0,0001

2-3 p = 0,1200

BMI [kg/m²]

34,9 ± 4,5

27,7 ± 4,4

23,9 ± 2,8

1-2 p = 0,0002

1-3 p = 0,0001

2-3 p = 0,0598

Waist circumference [cm]

113,1 ± 11,6

100,5 ± 13,5

81,4 ± 9,6

1-2 p = 0,0168

1-3 p = 0,0001

2-3 p = 0,0003

Serum fasting glucose [mg/dl]

99,5 ± 14,2

100,6 ± 24,0

83,5 ± 8,4

1-2 p = 0,9807

1-3 p = 0,0011

2-3 p = 0,0103

Total cholesterol[mg/dl]

195,1 ± 40,5

198,4 ± 35,1

210,4 ± 48,9

p = ns

HDL [mg/dl]

47,5 ± 13,4

49,6 ± 14,9

59,8 ± 19,6

1-2 p = 0,9360

1-3 p = 0,0225

2-3 p = 0,2184

TG [mg/dl]

126 (57 – 1242)

119 (61 – 1242)

96 (54 – 142)

1-2 p = 1,0000

1-3 p = 0,0040

2-3 p = 0,1264

Serum uric acid [mg/dl]

5,72 ± 1,11

7,26 ± 2,21

4,52 ± 0,96

1-2 p = 0,0092

1-3 p = 0,0059

2-3 p = 0,0001

CRP [ng/l]

2,36 (0,27-106)

2,43 (0,20-41,9)

0,70 (0,11-17,81)

1-2 p = 1,0000

1-3 p = 0,0016

2-3 p = 0,0167

eGFR (MDRD equation) [ml/min]

95,1 ± 15,2

52,4 ± 21,0

98,5 ± 19,6

1-2 p = 0,0001

1-3 p = 0,7730

2-3 p = 0,0001

Serum creatinine[mg/dl]

0,81 ± 0,19

1,35 ± 0,38

0,78 ± 0,18

1-2 p = 0,0001

1-3 p = 0,9230

2-3 p = 0,0001

Urine uric acid mg/24 h

665 ± 350

340 ± 121

535 ± 196

1-2 p = 0,0070

1-3 p = 0,2217

2-3 p = 0,1507

Urine sodium mmol/l

135,9 ± 52,3

87,0 ± 39,9

96,6 ± 44,1

1-2 p = 0,0222

1-3 p = 0,0129

2-3 p = 0,8552

Urine sodium g/24 h

5,50 ± 2,22

4,15 ± 2,29

3,87 ± 1,52

1-2 p = 0,1865

1-3 p = 0,0157

2-3 p = 0,9310

Microalbuminuria/g creatinine

4,8 (1,3-830)

41,3 (3,7-2656)

4,2 (2,3-10,1)

1-2 p = 0,0146

1-3 p = 1,0000

2-3 p = 0,0021