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Fig. 7 | BMC Nephrology

Fig. 7

From: Pathogenic pathways are activated in each major cell type of the glomerulus in the Cd2ap mutant mouse model of focal segmental glomerulosclerosis

Fig. 7

Immunostain validations of differential expression. Top panels show elevated expression of Frem1 in podocytes (MafB positive) cells of the glomerulus. Arrows show two cells with higher Frem1 levels in mutants. Middle panels show elevated expression of Lmx1b in wildtype podocytes. Arrows mark two cells with increased Lmx1b expression. Bottom panels show elevated expression of thrombospondin (Thsb1) in mutant mesangial cells

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