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Table 2 Distribution of preoperative and operative data according to occurence or not of AKI allocated to RIFLE (Risk, Injury and Failure grade) and by the serum creatinine (SCr) or urine output (UO) criteria AKI

From: Incidence and outcomes of acute kidney injury after cardiac surgery using either criteria of the RIFLE classification

Variable

No AKI

AKI

p-value

AKI SCr

AKI UO

p-value

(N = 222)

(N = 221)

(N = 43)

(N = 178)

Age (years)

65.0 (59.0 - 74.0)

71.0 (63.0 - 73.0)

< 0.001

71.0 (60.0 - 77.0)

71.0 (63.0 - 77.0)

0.98

Gender (Female) (%)

61 (27.5)

72 (32.5)

0.21

12 (27.9)

60 (33.7)

0.47

BMI (kg/m²)

25.6 (22.9 - 28.3)

26.9 (24.3 - 30.5)

< 0.001

28.3 (24.8 - 30.9)

26.6 (24.4 - 30.4)

0.25

Hypertension (%)

178 (80.2)

173 (78.3)

0.62

40 (93.0)

133 (74.7)

< 0.001

COPD (%)

39 (17.6)

45 (20.4)

0.45

14 (32.6)

31 (17.4)

0.03

Angina pectoris (%)

106 (47.7)

91 (41.2)

0.16

16 (37.2)

75 (42.1)

0.55

MI previous surgery (%)

67 (30.2)

49 (22.2)

0.06

10 (23.3)

39 (21.9)

0.85

Diabetes mellitus (%)

44 (19.8)

56 (25.3)

0.16

14 (32.6)

42 (23.6)

0.22

Emergency (%)

8 (3.60)

4 (1.81)

0.24

0 (0.00)

4 (2.25)

0.32

Preoperative GFR

      

 (mL/min)

83.0 (73 - 97)

72.0 (56 - 89)

< 0.001

67.0 (49 - 78)

73.5 (56 - 89)

0.06

Preoperative

      

 Hemoglobin (g/dL)

14.0 (12.7 - 14.9)

13.5 (12.4 - 14.7)

0.10

12.9 (11.5 - 14.6)

13.8 (12.5 - 14.8)

0.06

LVEF < 60% (%)

58 (26.1)

56 (25.3)

0.85

13 (30.2)

43 (24.2)

0.41

Logistic

      

 Parsonnet (%)

5.12 (2.65 - 10.8)

7.60 (4.05 - 17.3)

< 0.001

8.41 (5.16 - 15.9)

7.47 (4.00 - 18.7)

0.71

Logistic

      

 EuroSCORE1 (%)

3.51 (2.01 - 6.48)

4.79 (2.28 - 8.58)

0.004

5.29 (2.73 - 11.0)

4.65 (2.21 - 8.44)

0.40

Surgical delay (days)

20.0 (6 - 39)

22.0 (8 - 45)

0.18

17.0 (5 - 35)

27.0 (8 - 48)

0.02

Type of surgery

      

 OPCABG (%)

37 (16.7)

21 (9.50)

< 0.001

6 (14.0)

15 (8.43)

0.13

 CABG (%)

102 (45.9)

80 (36.1)

 

13 (30.2)

67 (37.6)

 

 Valve surgery (%)

74 (33.3)

74 (33.5)

 

19 (44.2)

55 (30.9)

 

 Valve and CABG (%)

9 (4.05)

46 (20.8)

 

5 (11.6)

41 (23.0)

 

CPB time (min.)*

85.0 (70 - 100)

90.0 (75.5 - 108.0)

0.02

89.0 (81.0 - 100.0)

90.0 (74.0 - 109.0)

0.80

Aortic cross

      

 Clamp time (min.)*

52.0 (39.0 - 64.0)

58.0 (44.0 - 75.0)

0.003

58.0 (45.0 - 71.0)

58.5 (43.5 - 76.0)

0.83

Nadir hematocrit (%)

22.0 (19 - 24)

20.0 (19 - 24)

0.06

20.0 (19.0 - 24.0)

20.0 (19.0 - 24.0)

0.83

Nadir MAP

      

 During surgery (mmHg)

45 (40 -55)

45 (40 -55)

0.57

45 (40 -55)

45 (40 -50)

0.50

Days in ICU

2.0 (2 - 3)

2.0 (2 -4)

< 0.001

3.0 (2 - 6)

2.0 (2 - 4)

0.07

Days in hospital

12.0 (10 - 16)

13.0 (10 - 18)

0.55

14.0 (11 - 22)

12.0 (10 - 18)

0.07

  1. Data are expressed as median (25-75th percentiles) or proportion of patients in %
  2. *Data are calculated as median (25-75th percentiles) only for cases with cardiopulmonary bypass (n = 385)
  3. BMI: body mass index; COPD: chronic obstructive pulmonary disease; MI: myocardial infarction; GFR: glomerular filtration rate; LVEF: left ventricular ejection fraction; Surgical delay: delay between diagnostic coronarography and surgery; OPCABG: off-pump coronary artery bypass graft; CABG: Coronary artery bypass graft with cardiopulmonary bypass; Valve surgery: aortic valve replacement or mitral valve repair/replacement surgery; Valve and CABG: aortic valve replacement or mitral valve repair/replacement surgery combined with coronary artery bypass graft; CPB: cardiopulmonary bypass; MAP: mean arterial pressure; ICU: intensive care unit
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BMC Nephrology

ISSN: 1471-2369

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