Table 1 Patients’ characteristics at presentation

General

Gender (% Male)

48

78

39

0.004

Age >65 years (%)

35

11

42

0.02

Age (years)

60 [53; 68]

58.0 [43; 62]

63 [55; 69]

0.01

Cold season at diagnosis

60 %

65 %

62 %

0.81

Time to diagnosis (mo)

2.0 [1.0; 5.6]

1.5 [1.0; 3.0]

2.0 [1.0; 6.0]

0.12

Vasculitis symptoms

Constitutional (%)

84

94

81

0.17

Skin (%)

9

17

7

0.22

Ocular (%)

3

11

0

0.01

Upper respiratory (%)

8

22

4

0.01

Lung (%)

48

50

47

0.85

Severe lung hemorrhage

31 %

39 %

28 %

0.39

Kidney (%)

100

100

100

1.00

Digestive (%)

4

0

5

0.32

CNS (%)

4

0

5

0.32

Organs affected (No)

2 [1; 2]

2 [1; 3]

2 [1; 2]

0.08

BVAS

17 [15; 21]

21 [15; 22]

17 [15; 20]

0.05

Inflammation

Hemoglobin (g/dL)

8.5 [7.5; 9.8]

7.7 [5.7; 9.5]

9.0 [7.8; 9.8]

0.04

Severe anemia (%)

35

56

28

0.03

WBC (per mm³)

9750 [7800; 14400]

10700 [7800; 15075]

9650 [7683; 13900]

0.64

ESR (mm/1 h)

97 [64; 120]

100 [80; 140]

94 [63; 120]

0.18

Fibrinogen (mg/dL)

680 [568; 800]

714 [608; 806]

670 [547; 800]

0.48

Serum albumin (mg/dL)

3.6 [3.10; 4.0]

3.3 [2.9; 3.7]

3.7 [3.1; 4.0]

0.15

Kidney disease

Histopathologic class

Crescentic (%)

52

67

47

0.52

Focal (%)

5

6

5

Mixed (%)

32

22

35

Sclerotic (%)

11

6

12

Creatinine (mg/dL)

5.0 [3.4; 7.9]

7.2 [4.2; 10.0]

4.8 [3.1; 7.2]

0.04

Proteinuria (g/day)

0.8 [0.5; 2.2]

1.0 [0.4; 1.4]

0.8 [0.5; 2.3]

0.73

Hematuria (per mm³)

260 [190; 800]

535 [288; 1200]

230 [183; 623]

0.005

Macroscopic hematuria

44 %

78 %

33 %

0.001

RBC casts (%)

37

72

28

0.02

Dialysis at presentation

27 %

50 %

19 %

0.01