Skip to main content

Advertisement

Table 4 Association of chronic kidney disease (CKD) with HBV, stratified by sex and age, with adjustment for competing mortality

From: 13-year nationwide cohort study of chronic kidney disease risk among treatment-naïve patients with chronic hepatitis B in Taiwan

  HBV cohort Non-HBV cohort   Hazard ratio (95 % CI)
  n PY CKD events n PY CKD events Crude P Adjusted* P
Sex
  Men 10428 68249 294 41712 274693 525 2.26 (1.96–2.61) <0.001 3.05 (2.50–3.71)† <0.001
  Women 7368 48243 131 29472 192357 297 1.77 (1.44–2.18) <0.001 2.56 (1.93–3.41)† <0.001
Age (year)
  < 50 13428 84358 203 53712 337813 191 4.30 (3.53–5.24) <0.001 2.86 (1.98–4.13) <0.001
  50 4368 32133 222 17472 129237 631 1.40 (1.20–1.63) <0.001 1.19 (0.90–1.56) 0.22
Men
  < 50 years 7888 49981 140 31552 200858 132 4.28 (3.38–5.43) <0.001 2.98 (2.32–3.83) <0.001
  50 years 2540 18268 154 10160 73835 393 1.57 (1.30–1.89) <0.001 1.58 (1.31–1.91) <0.001
Women
  < 50 years 5540 34378 63 22160 136955 59 4.34 (3.05–6.19) <0.001 2.99 (2.04–4.42) <0.001
  50 years 1828 13865 68 7312 55402 238 1.13 (0.86–1.48) 0.37 1.18 (0.90–1.55) 0.24
  1. Abbreviations: HBV hepatitis B virus, PY person-year, CI confidence interval
  2. *Adjusted for all covariates (age, sex, major comorbidities, use of herbs containing aristolochic acid, geographic region, urbanization level, enrollee category, number of medical visits, Charlson Comorbidity Index score, and propensity score) and interaction terms (HBV/age, HBV/sex, HBV/age/sex), minus the covariate and interaction terms on which stratified
  3. †Age was treated as a continuous variable in multivariate analysis