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Table 2 Factors associated with the occurrence of ACS

From: Pretransplant malnutrition, inflammation, and atherosclerosis affect cardiovascular outcomes after kidney transplantation

 

Univariate

Multivariatea

 

HR

95 % CI

p-value

HR

95 % CI

p-value

Age

1.08

1.03–1.12

0.001

1.05

1.01–1.10

0.008

Male

3.54

1.45–8.60

0.005

2.26

0.89–5.71

0.085

Smoking

1.92

0.77–4.78

0.162

   

BMI (continuous variable)

1.11

1.00–1.23

0.049

   

Hypertension

4.27

0.58–31.44

0.154

-

-

-

DM

3.55

1.78–7.05

<0.001

2.58

0.99–6.76

0.054

Dialysis before KT (vs. preemptive)

1.58

0.46–5.38

0.469

-

-

-

Dialysis vintage (months)

1.01

0.99–1.013

0.146

   

Cholesterol (<150 mg/dL)

1.46

0.69–3.07

0.324

   

Intact PTH

1.00

0.99–1.00

0.384

   

Recipient CMV IgG (+)

0.01

0.01–20.16

0.998

   

Donor sex (male)

0.64

0.31–1.29

0.208

-

-

-

Donor age

1.03

0.99–1.06

0.094

-

-

-

Deceased donor (vs. living donor)

2.72

1.12–6.61

0.027

2.17

0.80–5.91

0.128

Donor CMV IgG (+)

0.891

0.44–1.79

0.745

   

CsA (vs. tacrolimus)

1.9

0.91–3.95

0.085

-

-

-

NODAT

2.80

1.24–6.32

0.013

2.88

1.03–8.10

0.045

CMV disease

0.046

0.01–14.33

0.686

0.15

0.01–41.48

0.712

MIA factors

      

 Albumin (lowest quartile vs. others)

2.04

0.98–4.24

0.056

2.33

1.11–4.88

0.026

 CRP (highest quartile vs. others)

1.89

0.94–3.82

0.075

1.55

0.75–3.20

0.237

 Previous history of vascular diseasea

6.41

3.09–13.33

<0.001

2.61

1.08–6.27

0.033

MIA scorea

      

 0

Reference

Reference

 2

1.17

0.45–3.05

0.742

2.14

0.77–5.96

0.147

 4

2.51

0.79–8.03

0.121

1.86

0.39–8.73

0.436

 6

5.23

1.76–15.53

0.003

2.93

0.90–9.54

0.075

 8

7.53

2.28–24.85

0.001

3.11

0.73–13.29

0.125

 10

32.96

7.30–148.94

<0.001

34.29

8.29–141.84

<0.001

Group by MIA scorea

      

 0

Reference

Reference

 2–4

1.33

0.56–3.16

0.517

2.05

0.79–5.35

0.142

 6

5.28

1.78–15.68

0.003

3.06

0.94–9.99

0.063

 8–10

11.18

4.12–30.33

<0.001

6.12

1.84–20.32

0.003

  1. Data were analyzed by using the Cox regression, Backward LR method in the multivariate analysis
  2. ACS acute coronary syndrome, DM diabetes mellitus, KT kidney transplantation, NODAT new onset diabetes after transplantation, CsA cyclosporine A, Alb albumin
  3. aWe performed multivariate analysis about “MIA score”, “Previous history of vascular disease”, and “Group by MIA score” separately with other variables