Univariate | Multivariatea | |||||
---|---|---|---|---|---|---|
HR | 95 % CI | p-value | HR | 95 % CI | p-value | |
Age | 1.08 | 1.03–1.12 | 0.001 | 1.05 | 1.01–1.10 | 0.008 |
Male | 3.54 | 1.45–8.60 | 0.005 | 2.26 | 0.89–5.71 | 0.085 |
Smoking | 1.92 | 0.77–4.78 | 0.162 | |||
BMI (continuous variable) | 1.11 | 1.00–1.23 | 0.049 | |||
Hypertension | 4.27 | 0.58–31.44 | 0.154 | - | - | - |
DM | 3.55 | 1.78–7.05 | <0.001 | 2.58 | 0.99–6.76 | 0.054 |
Dialysis before KT (vs. preemptive) | 1.58 | 0.46–5.38 | 0.469 | - | - | - |
Dialysis vintage (months) | 1.01 | 0.99–1.013 | 0.146 | |||
Cholesterol (<150 mg/dL) | 1.46 | 0.69–3.07 | 0.324 | |||
Intact PTH | 1.00 | 0.99–1.00 | 0.384 | |||
Recipient CMV IgG (+) | 0.01 | 0.01–20.16 | 0.998 | |||
Donor sex (male) | 0.64 | 0.31–1.29 | 0.208 | - | - | - |
Donor age | 1.03 | 0.99–1.06 | 0.094 | - | - | - |
Deceased donor (vs. living donor) | 2.72 | 1.12–6.61 | 0.027 | 2.17 | 0.80–5.91 | 0.128 |
Donor CMV IgG (+) | 0.891 | 0.44–1.79 | 0.745 | |||
CsA (vs. tacrolimus) | 1.9 | 0.91–3.95 | 0.085 | - | - | - |
NODAT | 2.80 | 1.24–6.32 | 0.013 | 2.88 | 1.03–8.10 | 0.045 |
CMV disease | 0.046 | 0.01–14.33 | 0.686 | 0.15 | 0.01–41.48 | 0.712 |
MIA factors | ||||||
Albumin (lowest quartile vs. others) | 2.04 | 0.98–4.24 | 0.056 | 2.33 | 1.11–4.88 | 0.026 |
CRP (highest quartile vs. others) | 1.89 | 0.94–3.82 | 0.075 | 1.55 | 0.75–3.20 | 0.237 |
Previous history of vascular diseasea | 6.41 | 3.09–13.33 | <0.001 | 2.61 | 1.08–6.27 | 0.033 |
MIA scorea | ||||||
0 | Reference | Reference | ||||
2 | 1.17 | 0.45–3.05 | 0.742 | 2.14 | 0.77–5.96 | 0.147 |
4 | 2.51 | 0.79–8.03 | 0.121 | 1.86 | 0.39–8.73 | 0.436 |
6 | 5.23 | 1.76–15.53 | 0.003 | 2.93 | 0.90–9.54 | 0.075 |
8 | 7.53 | 2.28–24.85 | 0.001 | 3.11 | 0.73–13.29 | 0.125 |
10 | 32.96 | 7.30–148.94 | <0.001 | 34.29 | 8.29–141.84 | <0.001 |
Group by MIA scorea | ||||||
0 | Reference | Reference | ||||
2–4 | 1.33 | 0.56–3.16 | 0.517 | 2.05 | 0.79–5.35 | 0.142 |
6 | 5.28 | 1.78–15.68 | 0.003 | 3.06 | 0.94–9.99 | 0.063 |
8–10 | 11.18 | 4.12–30.33 | <0.001 | 6.12 | 1.84–20.32 | 0.003 |