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Table 1 Baseline characteristics of the cohort overall and stratified on relative and absolute interdialytic weight gain

From: A retrospective, longitudinal study estimating the association between interdialytic weight gain and cardiovascular events and death in hemodialysis patients

Variablea

Overall N = 39,256

Relative IDWG

Absolute IDWG

  

≤3.5 % n = 24,726

>3.5 % n = 14,530

p-value

≤3.0 kg n = 28,942

>3.0 kg n = 10,314

p-value

Age, year

62.2 ± 15.3

63.0 ± 15.0

60.7 ± 15.6

<0.001

63.7 ± (15.3

57.9 ± 14.2

<0.001

Female sex

17,238 (43.9)

11,462 (46.4)

5776 (39.8 %)

<0.001

14,180 (49.0)

3058 (29.7)

<0.001

Race

   

<0.001

  

<0.001

White

18,055 (46.0)

11,975 (48.5)

6080 (41.9)

 

13,358 (46.2)

4697 (45.6)

 

Black

12,437 (31.7)

7951 (32.2)

4486 (30.9)

9008 (31.1)

3429 (33.3)

Hispanic

5777 (14.7)

3153 (12.8)

2624 (18.1)

4279 (14.8)

1498 (14.5)

Asian

1260 (3.2)

635 (2.6)

625 (4.3)

1044 (3.6)

216 (2.1)

Other

984 (2.5)

586 (2.4)

398 (2.7)

742 (2.6)

242 (2.4)

ESRD etiology

   

<0.001

  

<0.001

Diabetes

18,500 (47.1)

11,068 (44.8)

7432 (51.2)

 

12,649 (43.7)

5851 (56.7)

 

Hypertension

11,942 (30.4)

7834 (31.7)

4108 (28.3)

9361 (32.3)

2581 (25.0)

Glomerular disease

2825 (7.2)

1927 (7.8)

898 (6.2)

2190 (7.6)

635 (6.2)

Other

5989 (15.3)

3897 (15.8)

2082 (14.4)

4742 (16.4)

1247 (12.1)

Prior renal txp

697 (1.8)

366 (1.5)

331 (2.3)

<0.001

507 (1.8)

190 (1.8)

0.55

Baseline diabetesb

26,768 (68.2)

16,337 (66.1)

10,431 (71.8)

<0.001

18,765 (64.8)

8003 (77.6)

<0.001

Baseline CHFb

15,623 (39.8)

9340 (37.8)

6283 (43.2)

<0.001

11,008 (38.0)

4615 (44.8)

<0.001

Baseline MIb

9920 (25.3)

6238 (25.2)

3682 (25.3)

0.81

7274 (25.1)

2646 (25.7)

0.30

Baseline AFb

2310 (5.9)

1433 (5.8)

877 (6.0)

0.33

1720 (5.9)

590 (5.7)

0.41

Baseline CVDc

3404 (8.7)

2129 (8.6)

1275 (8.8)

0.58

2560 (8.9)

844 (8.2)

0.04

Uncontrolled hypertensiond

37,283 (95.0)

23,492 (95.0)

13,791 (94.9)

0.68

27,464 (94.9)

9819 (95.2)

0.22

Vascular access

   

<0.001

  

<0.001

AVF

10,787 (27.7)

6826 (27.6)

4052 (27.9)

 

7728 (26.7)

3150 (30.6)

 

AVG

3782 (9.6)

2269 (9.2)

1513 (10.4)

2776 (9.6)

1006 (9.8)

CVC

24,573 (62.6)

15,616 (63.2)

8957 (61.7)

18,420 (63.7)

6153 (59.7)

Postdialysis weight, kg

77.0 (34.7)

80.3 (41.2)

71.4 (17.8)

<0.001

73.3 (37.2)

87.4 (23.5)

<0.001

  1. Abbreviations: AF atrial fibrillation, CHF congestive heart failure, CVD cerebrovascular disease, AVF arteriovenous fistula, AVG arteriovenous graft, CVC central venous catheter, ESRD end-stage renal disease, IDWG interdialytic weight gain, MI myocardial infarction, txp transplant
  2. aValues expressed as mean ± SD or n (%)
  3. bDefined based on CMS Medical Evidence Form 2728 data, claims (1 inpatient or 2 outpatient), or LDO EHR records prior to dialysis day 180
  4. cDefined based on CMS Medical Evidence Form 2728, claims (1 inpatient or 2 outpatient), LDO EHR record prior to dialysis day 180. Includes ischemic stroke, hemorrhagic stroke, and TIA
  5. dDefined as mean predialysis blood pressure > 140/90 mm Hg or postdialysis blood pressure > 130/85 mm Hg during the outcome period (dialysis days 91–180)
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BMC Nephrology

ISSN: 1471-2369

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