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Table 1 Baseline characteristics stratified by quartiles of urinary phosphorus per creatinine clearance

From: Urinary phosphorus excretion per creatinine clearance as a prognostic marker for progression of chronic kidney disease: a retrospective cohort study

 

All

Quartile 1

Quartile 2

Quartile 3

Quartile 4

P Value

(N = 175)

≤ 11.15

11.16–17.07

17.08–29.61

≥ 29.62

(N = 44)

(N = 44)

(N = 43)

(N = 44)

Age

65.4 ± 12.3

67.4 ± 14.1

66.9 ± 11.0

66.9 ± 9.64

61.1 ± 13.1

0.07

Male sex (n, %)

120 (68.5)

35 (79.6)

31 (70.5)

26 (60.5)

28 (63.6)

0.21

Body mass index

23.6 ± 3.58

23.2 ± 3.82

23.7 ± 3.75

23.1 ± 3.64

24.2 ± 3.07

0.44

Diabetes mellitus (n, %)

59 (33.7)

15 (34.1)

14 (32.6)

18 (32.6)

18 (40.9)

0.60

Protein intake (g/day)

36.8 ± 10.78

41.1 ± 13.7

35.0 ± 8.97

33.0 ± 9.00

37.9 ± 9.24

0.10

Cr (mg/dL)

3.73 ± 2.22

1.70 ± 0.56

2.68 ± 1.01

3.83 ± 1.13

6.71 ± 1.70

< 0.001

estimated GFR (ml/min/1.73 m2)

19.1 ± 13.5

35.3 ± 14.3

20.7 ± 7.34

13.0 ± 4.18

7.34 ± 2.77

< 0.001

CKD stage G2 (n,%)

4 (2.3)

4 (9.1)

0 (0.0)

0 (0.0)

0 (0.0)

 

G3a (n,%)

4 (2.3)

4 (9.1)

0 (0.0)

0 (0.0)

0 (0.0)

 

G3b (n,%)

26 (14.9)

21 (47.7)

5 (11.4)

0 (0.0)

0 (0.0)

 

G4 (n,%)

55 (31.4)

13 (29.5)

27 (61.4)

13 (30.2)

2 (45.5)

 

G5 (n, %)

86 (49.1)

2 (4.5)

12 (27.3)

30 (69.8)

42 (95.5)

 

24-h-CCr (ml/min)

24.7 ± 22.1

49.4 ± 28.7

24.7 ± 12.1

14.6 ± 5.93

9.83 ± 3.66

< 0.001

Corrected Ca (mg/dL)

9.41 ± 0.63

9.72 ± 0.44

9.57 ± 0.51

9.39 ± 0.51

8.96 ± 0.75

< 0.001

Serum phosphorus (mg/dL)

4.20 ± 1.07

3.50 ± 0.57

3.76 ± 0.58

4.19 ± 0.82

5.35 ± 1.14

< 0.001

iPTH (pg/mL)

139.0 ± 134.1

54.8 ± 27.8

95.7 ± 52.2

156.3 ± 114.3

261.5 ± 186.6

< 0.001

1,25(OH)VitD (pg/mL)

24.7 ± 22.1

36.9 ± 16.9

26.1 ± 10.9

22.0 ± 9.9

13.0 ± 6.1

< 0.001

Urinary protein (g/day)

2.15 ± 2.46

1.18 ± 1.98

1.86 ± 2.03

1.94 ± 1.93

3.63 ± 3.07

< 0.001

Urinary phosphorus (mg/day)

356 ± 158

393 ± 201

342 ± 163

310 ± 114

379 ± 129

0.06

  1. Data are means ± SD or n (% of total), Comparisons were made by χ2 test or analysis of variance (ANOVA). Continuous variables were expressed as mean ± standard deviation (SD), and categorical variables were expressed as proportions. Categorical variables were tested by χ2 test, and continuous variables were compared by ANOVA. The homogeneity of the variances was analyzed by the Leven test; in those cases in which the variances were unequal, the variables were compared by Welch’s test. Cr, serum creatinine levels; GFR, glomerular filtration rate; 24-h-CCr, 24-h creatinine clearance; Ca, calcium; iPTH, intact parathormone; 1,25(OH)VitD, 1,25 dihydroxyvitaminD