Fig. 1

Microscopy results of kidney and liver tissue from a 60-year-old man with myeloproliferative neoplasm-related glomerulopathy in the early stages of primary myelofibrosis hematoxylin and eosin (H&E) (a) and periodic acid-Schiff (PAS) (b) stained sections of glomeruli with moderate mesangial matrix expansion and occasional intracapillary and intra-arteriolar megakaryocytes (arrows). The renal tubulointerstitium (c) also contained interstitial or intracapillary megakaryocytes (arrow). A biopsy of the liver (d) showed megakaryocytes, nucleated red blood cells and other immature myeloid cell within the hepatic sinusoids