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Table 3 Summary statistics of primary endpoint (the difference in the 1/SCr versus time slope between run-in period [R0 ~ R20] and treatment period [W4 ~ W28])

From: Orally active prostacyclin analogue beraprost sodium in patients with chronic kidney disease: a randomized, double-blind, placebo-controlled, phase II dose finding trial

Treatment group

No. of patients

1/SCr versus time slope (dL/mg over 4 weeks)

Difference in the 1/SCr versus time slope (dL/mg over 4 weeks)

  

Run-in period (R0 ~ R20)

Treatment period (W4 ~ W28)

  
  

Mean

SD

Mean

SD

Mean

SD

Placebo

34

−0.0121

0.00497

−0.0074

0.00935

0.0047

0.01087

120 μg

32

−0.0154

0.00808

−0.0040

0.01345

0.0113

0.01011

240 μg

36

−0.0120

0.00788

−0.0045

0.00750

0.0075

0.00953