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Table 4 Quarterly mortality among ESA responders, acute hyporesponders and chronic hyporesponders

From: Characterization of chronic and acute ESA hyporesponse: a retrospective cohort study of hemodialysis patients

 

Chronic Hyporesponders

Acute Hyporesponders

ESA Responders

P Value

Q1 (Months 5–7) % deaths

5.48 % (169/3086)

2.97 % (197/6632)

2.00 % (1631/81,504)

<0.0001

Q2 (Months 8–10) % deaths

4.56 % (125/2741)

3.06 % (189/6167)

2.16 % (1671/77,451)

<0.0001

Q3 (Months 11–13) % deaths

4.61 % (115/2497)

3.30 % (186/5723)

2.49 % (1834/73,559)

<0.0001

Q4 (Months 14, 15) % deaths

2.98 % (67/2250)

2.17 % (116/5334)

1.43 % (997/69,478)

<0.0001

  1. Quarterly mortality was calculated by dividing the total number of deaths over the time period divided by the number of patients alive at the beginning of the time period who were not censored for discontinuation, modality change, or transplant/failed transplant. To avoid immortal time bias, mortality was considered beginning in month 5 (i.e., after the distinction between acute and chronic ESA hyporesponsiveness could be made); patients who died or were censored before 4 months had elapsed were excluded from analyses
  2. P values represent a chi square test
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BMC Nephrology

ISSN: 1471-2369

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