Assessment of urinary kidney injury molecule-1 and interleukin-18 in the early post-burn period to predict acute kidney injury for various degrees of burn injury

Table 1 Patient data for the control group and burn groups

	Control (n = 15)	Mild burn (n = 37)	Moderate burn (n = 30)	Severe burn (n = 28)	p value
M/F	11/4	29/8	23/7	23/5	0.481
Age (y)	38.5 ± 10.2	31.5 ± 15.5	35.7 ± 18.4	40.6 ± 14.8	0.121
TBSA (%)	/	7.01 ± 1.61	24.9 ± 3.48	44.4 ± 13.8	/
BUN (mmol/L)	4.14 ± 0.87	4.91 ± 1.53	4.79 ± 1.71	4.88 ± 0.88	0.161
Scr (μmol/L)	59.0 ± 8.73	54.6 ± 20.8	60.9 ± 20.9	60.9 ± 18.4	0.476
Urinary KIM-1 (ng/mL)	2.12 ± 0.80	2.65 ± 0.73	4.06 ± 1.38^ab	5.06 ± 1.51^abc	0.000
Urinary IL-18 (pg/mL)	6.04 ± 1.41	6.27 ± 2.84	6.93 ± 3.11	6.68 ± 2.66	0.671

Data expressed as mean ± standard deviation unless otherwise indicated. Alb, albumin; BUN, blood urea nitrogen; F, female; IL-18, interleukin-18; KIM-1, kidney injury molecule-1; M, male; Scr, serum creatinine; TBSA, total burn surface area
^avs. control group; ^bvs. mild-burn group; ^cvs. moderate-burn group

ISSN: 1471-2369