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Table 2 Clinical features and laboratory results of non-AKI and AKI groups

From: Assessment of urinary kidney injury molecule-1 and interleukin-18 in the early post-burn period to predict acute kidney injury for various degrees of burn injury

 

Non-AKI group (n = 47)

AKI group (n = 11)

p value

At the time of admission

Age (y)

39.1 ± 17.7

33.4 ± 11.3

0.309

gender (M/F)

39/8

7/4

0.154

TBSA (%)

32.0 ± 10.1

44.2 ± 22.4a

0.008

Third-degree burn area (%)

5(0,14)

27(9,48)

0.000

Inhalation injury,n (%)

6(12.8)

7(63.6)

0.000

Rhabdomyolysis,n (%)

5(10.6)

6(54.5)

0.001

BUN (mmol/L)

4.52 ± 1.14

7.02 ± 1.53

0.000

Scr (μmol/L)

55.2 ± 14.1

85.3 ± 21.6

0.000

Urinary KIM-1 (ng/mL)

4.23 ± 1.25

5.84 ± 1.89

0.001

Urinary IL-18 (pg/mL)

6.15 ± 2.57

9.64 ± 2.43

0.000

APACHE II Score

8.34 ± 5.84

16.3 ± 7.35a

0.000

48 h after admission

BUN (mmol/L)

5.52 ± 1.45

11.4 ± 2.99

0.000

Scr (μmol/L)

57.4 ± 15.0

178.4 ± 58.8

0.000

U KIM-1 (ng/mL)

4.62 ± 1.25

6.18 ± 1.62

0.001

UIL-18 (pg/mL)

5.80 ± 2.16

10.9 ± 2.86

0.000

Mechanical ventilation,n (%)

0

5(45.5)

/

CRRT,n (%)

0

5(45.5)

/

APACHE II Score

8.36 ± 6.38

29.3 ± 7.77a

0.000

Wihtin 4 weeks

   

Mortality,n (%)

0

4(36.4)

/

  1. APACHE II, Acute Physiology and Chronic Health Evaluation II; BUN, blood urea nitrogen; CRRT, continuous renal replacement therapy; IL-18, interleukin-18; KIM-1, kidney injury molecule-1; Scr, serum creatinine; TBSA, total burn surface area
  2. aAKI group vs. non-AKI group