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Table 2 Relationship between independent variables and proportion of appropriately adjusted prescription entries per patient in Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia, August 2013

From: Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia

Variables

All medications per patient were inappropriately adjusted

P-value

OR (95 %) CI

 

Yes

No

 

COR

AOR

Sex

Male

10

19

 

1.00

1.00

Female

7

18

0.446

0.74 (0.23,2.36)

0.35 (0.04,3.35)

Age

18-29

6

9

0.281

1.00

1.00

30-39

1

4

0.551

0.56 (0.11,3.02)

0.59 (0.03,14.21)

40-49

4

6

0.424

1.50 (0.12,19.44)

2.92 (0.06,127.78)

50-59

3

10

0.667

0.56 (0.09,3.52)

0.42 (0.023,7.677)

≥60

3

8

0.043

1.25 (0.196,7.96)

0.58 (0.03,10.10)

Stage

Stage 3

8

31

-

1.00

1.00

Stage 4

7

4

0.99

3.88 (0.471,31.91)

0.73 (0.00,715.2)

Stage 5

2

2

0.99

0.57 (0.06,5.78)

0.10 (0.00,20.32)

Weight (mean)

62.88

59.59

0.221

0.98 (0.93,1.03)

1.03 (0.92,1.16)

SCr (mean)

3.27

1.88

0.898

0.51 (0.31,0.84)a

0.19 (0.03,1.25)

BUN (mean)

103.56

80.38

0.053

0.99 (0.98,1.00)

1.03 (0.99,1.06)

Reason of admission

Renal

7

7

0.45

1.00

1.00

Non renal

10

30

 

0.33(0.09,1.18)

0.89 (0.08,10.03)

Comorbidity

Present

14

32

-

1.00

1.00

Absent

3

5

0.109

1.37 (0.29,6.55)

0.31 (0.02,5.29)

No of Med prescribed Per patient (mean)

4.41

6.03

0.234

1.39 (1.04,1.89)a

1.39 (0.89,2.19)

-No of Med need Dose adjustment per patient (mean)

1.76

2.30

0.17

1.75 (0.89,3.46)

1.57(0.54,4.55)

  1. astatistically significant; COD crude odds ratio; AOR adjusted odds ratio