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Table 2 Relationship between independent variables and proportion of appropriately adjusted prescription entries per patient in Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia, August 2013

From: Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia

Variables All medications per patient were inappropriately adjusted P-value OR (95 %) CI
  Yes No   COR AOR
Sex
Male 10 19   1.00 1.00
Female 7 18 0.446 0.74 (0.23,2.36) 0.35 (0.04,3.35)
Age
18-29 6 9 0.281 1.00 1.00
30-39 1 4 0.551 0.56 (0.11,3.02) 0.59 (0.03,14.21)
40-49 4 6 0.424 1.50 (0.12,19.44) 2.92 (0.06,127.78)
50-59 3 10 0.667 0.56 (0.09,3.52) 0.42 (0.023,7.677)
≥60 3 8 0.043 1.25 (0.196,7.96) 0.58 (0.03,10.10)
Stage
Stage 3 8 31 - 1.00 1.00
Stage 4 7 4 0.99 3.88 (0.471,31.91) 0.73 (0.00,715.2)
Stage 5 2 2 0.99 0.57 (0.06,5.78) 0.10 (0.00,20.32)
Weight (mean) 62.88 59.59 0.221 0.98 (0.93,1.03) 1.03 (0.92,1.16)
SCr (mean) 3.27 1.88 0.898 0.51 (0.31,0.84)a 0.19 (0.03,1.25)
BUN (mean) 103.56 80.38 0.053 0.99 (0.98,1.00) 1.03 (0.99,1.06)
Reason of admission
Renal 7 7 0.45 1.00 1.00
Non renal 10 30   0.33(0.09,1.18) 0.89 (0.08,10.03)
Comorbidity
Present 14 32 - 1.00 1.00
Absent 3 5 0.109 1.37 (0.29,6.55) 0.31 (0.02,5.29)
No of Med prescribed Per patient (mean) 4.41 6.03 0.234 1.39 (1.04,1.89)a 1.39 (0.89,2.19)
-No of Med need Dose adjustment per patient (mean) 1.76 2.30 0.17 1.75 (0.89,3.46) 1.57(0.54,4.55)
  1. astatistically significant; COD crude odds ratio; AOR adjusted odds ratio