Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease

BMC Nephrology

Table 6 Hazard ratios (HR) and 95 % confidence intervals (CI) for renal replacement therapy. Predictors are baseline variables

		Model 1a and b			Model 2			Model 3			Model 4
		HR	95 % CI	P value	HR	95 % CI	P value	HR	95 % CI	P value	HR	95 % CI	P value
SIMD quintiles	V	Ref.			Ref.			Ref.			Ref.
	IV	1.03	0.51-2.05	0.94	1.04	0.52–2.09	0.90	1.02	0.51–2.06	0.95	1.47	0.68–3.19	0.33
	III	0.81	0.38-1.70	0.58	0.83	0.39–1.75	0.62	0.84	0.40–1.79	0.66	1.03	0.45–2.37	0.94
	II	0.44	0.21-0.95	0.037	0.43	0.20–0.93	0.032	0.47	0.22–1.00	0.051	0.47	0.20–1.12	0.087
	I	1.16	0.63-2.10	0.64	1.18	0.65–2.16	0.59	1.12	0.60–20.08	0.73	1.01	0.51–2.01	0.98
Phosphate groups	<0.90 mmol/L	0.77	0.25–2.34	0.64	0.82	0.27–2.52	0.73	1.02	0.33–3.16	0.97	0.95	0.26–3.46	0.94
	0.90–1.09 mmol/L	Ref.			Ref.			Ref.			Ref.
	1.10–1.29 mmol/L	1.16	0.58–2.29	0.68	1.22	0.61–2.41	0.57	1.37	0.68–2.75	0.38	1.13	0.53–2.43	0.76
	1.30–1.49 mmol/L	1.83	0.94–3.58	0.077	1.76	0.90–3.46	0.098	2.12	1.06–4.24	0.034	1.53	0.72–3.27	0.76
	≥1.50 mmol/L	2.29	1.12–4.71	0.024	2.51	1.24–5.10	0.011	3.03	1.43-6.42	0.004	1.64	0.71-3.82	0.25

eGFR, Estimated glomerular filtration rate according to the CKD‐EPI equation, SIMD Scottish index of multiple deprivation. Quintile I comprise the most deprived and quintile V the least deprived. PCR Protein‐creatinine ratio, Model 1a SIMD quintiles, eGFR Age and sex, Model 1b Phosphate groups, eGFR Age and sex, Model 2 SIMD quintiles, phosphate groups, eGFR Age and sex, Model 3 Model 2 plus traditional cardiovascular risk factors (presence of diabetes and/or coronary heart disease, systolic and diastolic blood pressure, body weight), Model 4 Model 3 plus non‐traditional risk factors (urinary PCR, serum albumin, haemoglobin)

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