Fig. 1

a-b. Bland-Altman-plots of eGFR determined by Creatinine (Cr)- and Cystatin C (CysC)-based equations. a Compared to mGFR, the commonly used Cr-based equations MDRD and CKD-EPI-Cr show less agreement with the gold standard in cirrhotic patients (a, upper panel) as compared to healthy controls (a, lower panel). b Compared to the Cr-based equations MDRD and CKD-EPI-Cr, the CKD-EPI-CysC equation shows a better performance in cirrhosis and an almost similar agreement with sinistrin clearance in cirrhotic patients (b, upper panel) and healthy controls (b, lower panel). a-b Horizontal long-dashed lines depict the bias (average difference between mGFR and eGFR), short-dashed lines show the limits of agreement between mGFR and eGFR according to the Bland-Altman method, and filled circles denote the measurement points. The oblique straight lines show the regression line between difference and average, and the shaded areas show the hyperbolic 95 % confidence limits of this regression line. R-values represent the Pearson’s linear correlation coefficients between difference and average. MDRD, Modification of Diet in Renal Disease; CKD-EPI, Chronic kidney disease epidemiology collaboration; Cr, Creatinine; CysC, Cystatin C