Fig. 2

Bland-Altman-plots of eGFR determined by the combined CKD-EPI-Cr-CysC equation. Bland-Altman-plots of the CKD-EPI-Cr-CysC equation compared to mGFR determined by sinistrin clearance show an excellent agreement between eGFR and mGFR for the combined equation. The agreement between mGFR and eGFR using the combined formula in cirrhotic patients (a) is as good as that in healthy controls (b). a-b Horizontal long-dashed lines depict the bias (average difference between mGFR and eGFR), short-dashed lines show the limits of agreement between mGFR and eGFR according to the Bland-Altman method, and filled circles denote the measurement points. The oblique straight lines show the regression line between difference and average, and the shaded areas show the hyperbolic 95 % confidence limits of this regression line. R-values represent the Pearson’s linear correlation coefficients between difference and average. CKD-EPI, Chronic kidney disease epidemiology collaboration; Cr, Creatinine; CysC, Cystatin C